Results 1 to 10 of about 138,961 (205)

Food oral immunotherapy [PDF]

Allergy, Asthma & Clinical Immunology
Food oral immunotherapy (OIT) is an option for the treatment of immunoglobin E (IgE)‐mediated food allergy that involves administering gradually increasing doses of an allergenic food over time (under medical supervision) with the goal of desensitizing ...
Mary McHenry, Philippe Bégin, Edmond S. Chan, Meriem Latrous, Harold Kim   +4 more
doaj   +4 more sources

Oral immunotherapy for cow’s milk allergy in children: a systematic review and meta-analysis [PDF]

Frontiers in Immunology
ObjectiveCow’s milk allergy (CMA) is one of the most common causes of food allergies (FA) in children. There have been studies on the use of immunotherapy in cow’s milk protein allergy, with oral immunotherapy (OIT) being the most extensively researched.
Yan Wang, Yan Wang, Shunli Liu, Shunli Liu, Meizhu Lu, Meizhu Lu, Jingyu Guo, Jingyu Guo, Can Lv, Can Lv, Lan Huang, Lan Huang   +11 more
doaj   +2 more sources

Trends in allergen-reactive CRTH2+ T cells and TARC associated with successful outcomes in a phase 2 cashew oral immunotherapy study [PDF]

Frontiers in Immunology
BackgroundWe designed an oral immunotherapy (OIT) clinical trial for cashew allergy to further our understanding of immunological responses with treatment, including changes in allergen-specific T cells.
Sayantani B. Sindher, Andrea Fernandes, Monali Manohar, Shu Cao, Sheena Gupta, Sheena Gupta, Ella Parsons, Dinara Bogetic, Divya Kumar, Jessica Rogers, Julia Thompson, Diane Dunham, Evan Do, Sofia Maysel-Auslender, Taryn Audrey Liu, Kristine Martinez, Brent Anderson, Abhinav Kaushik, Manisha Desai, Holden Maecker, Holden Maecker, Susan Perry, Lisa M. Wheatley, Kari C. Nadeau, Kari C. Nadeau, R. Sharon Chinthrajah   +25 more
doaj   +2 more sources

Real-life safety of peanut oral immunotherapy: Results from a French multicenter observational study [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: Peanut oral immunotherapy (POIT) has been widely used in France for more than 10 years. However, the overall “real-life” safety of POIT has not been evaluated to date.
Elodie Michaud, MD, Flore Amat, MD, PhD, Dr Habil, Céline Lambert, MSc, Amandine Divaret-Chauveau, PhD, Antoine Deschildre, Pr, A. Nemni, M. Voidey, T. Moraly, P. Bierme, D. Sabouraud, L. Couderc, D. Caimmi, A. Dupré Latour   +12 more
doaj   +2 more sources

Safer oral immunotherapy with very low-dose introduction for pediatric hen’s egg allergy [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: Adverse events could be a barrier to implementing oral immunotherapy (OIT) in children with hen’s egg (HE) allergy, highlighting the need for safer OIT methods.
Fumi Ishikawa, MD, Yumiko Miyaji, MD, PhD, Kiwako Yamamoto-Hanada, MD, PhD, Mami Shimada, MD, Tomoyuki Kiguchi, MD, Seiko Hirai, MD, Yuri Endo Kram, MD, Kazuma Takada, MD, Kyoko Noguchi, MD, Yusuke Inuzuka, MD, Kenji Toyokuni, MD, PhD, Mayako Saito-Abe, MD, PhD, Miori Sato, MD, Shigenori Kabashima, MD, PhD, Kyongsun Pak, PhD, Eisuke Inoue, PhD, Tatsuki Fukuie, MD, PhD, Yukihiro Ohya, MD, PhD   +17 more
doaj   +2 more sources

Elucidation of Desensitization Mechanisms Induced by Oral Immunotherapy in a Rat Model of Ovalbumin Allergy [PDF]

Foods
Oral immunotherapy (OIT) is a promising approach for treating food allergy. Here, we elucidated the mechanisms of desensitization induced by OIT in rats sensitized to ovalbumin (OVA).
Daigo Takizawa, Tomoharu Yokooji, Chika Miyamoto, Yuki Koga, Keisuke Oda, Ryohei Ogino, Takanori Taogoshi, Hiroaki Matsuo   +7 more
doaj   +2 more sources

Knocking-Down CD147/EMMPRIN Expression in CT26 Colon Carcinoma Forces the Cells into Cellular and Angiogenic Dormancy That Can Be Reversed by Interactions with Macrophages

Biomedicines, 2023
Metastasis in colorectal cancer is responsible for most of the cancer-related deaths. For metastasis to occur, tumor cells must first undergo the epithelial-to-mesenchymal transition (EMT), which is driven by the transcription factors (EMT-TFs) Snail ...
Gabriele Feigelman, Elina Simanovich, Phillipp Brockmeyer, Michal A. Rahat   +3 more
doaj   +1 more source

Oral immunotherapy in children for the most common food allergy

Studia Medyczne, 2022
Nowadays, the incidence of food allergies is increasing. While strict allergen avoidance remains the most important therapeutic approach, oral immunotherapy is increasingly being used to desensitize and induce tolerance in children. Oral immunotherapy is
Adrianna Kruczkowska, Andrzej Kanturski, Bartosz Tomczyk, Mateusz Wilk, Jakub Ptak, Krzysztof Gomułka   +5 more
doaj   +1 more source

Immunology of Oral Squamous Cell Carcinoma—A Comprehensive Insight with Recent Concepts

Life, 2022
This review aims to understand the concept of oral cancer immunology through the notion of immune profiling, immunoediting and immunotherapy, and to gain knowledge regarding its application for the management of oral cancer patients.
Sowmya Samudrala Venkatesiah, Dominic Augustine, Deepika Mishra, Neethi Gujjar, Vanishri C. Haragannavar, Kamran Habib Awan, Shankargouda Patil   +6 more
doaj   +1 more source

Oral Immunotherapy for Cow"s Milk Allergy: Five Years" Experience from a Single Center in Turkey

Balkan Medical Journal, 2020
Background: Oral immunotherapy for cow’s milk allergy is an effective treatment option because of its ability to increase the threshold for clinical reactions. Aims: To present our experience of oral immunotherapy for cow’s milk allergy in the pediatric
Esen Demir, Nursen Ciğerci Günaydın, Figen Gülen, Remziye Tanaç   +3 more
doaj   +1 more source