Results 21 to 30 of about 138,961 (205)

Children and caregiver proxy quality of life from peanut oral immunotherapy trials

Clinical and Translational Allergy, 2022
Background Health‐related quality of life (HRQoL) is significantly and substantially reduced in individuals with peanut allergy due to many factors associated with unanticipated or potentially fatal reactions. Further insight on the impact of peanut oral
Audrey Dunn Galvin, Andrea Vereda, Pablo Rodríguez delRío, Antonella Muraro, Carla Jones, Robert Ryan, David Norval, Jennifer Jobrack, Aikaterini Anagnostou, Julie Wang   +9 more
doaj   +1 more source

Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy [PDF]

, 2011
Background: The treatment of high-risk neuroblastoma patients consists of multimodal induction therapy to achieve remission followed by consolidation therapy to prevent relapses. However, the type of consolidation therapy is still discussed controversial.
Simon, Thorsten, Hero, Barbara, Faldum, Andreas, Handgretinger, Rupert, Schrappe, Martin, Klingebiel, Thomas, Berthold, Frank   +6 more
core   +1 more source

Bronchial hyperresponsiveness and asthma during oral immunotherapy for egg or peanut allergy in children

Clinical and Translational Allergy, 2022
Background Bronchial hyperresponsiveness (BHR) and asthma are frequently present in children with food allergy. We assessed BHR in children receiving oral immunotherapy (OIT) for persistent egg or peanut allergy and examined whether OIT affects asthma ...
Janne Burman, Kati Palosuo, Anna Pelkonen, Pekka Malmberg, Sami Remes, Kaarina Kukkonen, Mika J. Mäkelä   +6 more
doaj   +1 more source

Progress of Home-Based Food Allergy Treatment during the Coronavirus Disease Pandemic in Japan: A Cross-Sectional Multicenter Survey

Children, 2021
The coronavirus disease 2019 (COVID-19) pandemic’s impact on food allergy treatment such as home-based oral immunotherapy (OIT) is not known. This cross-sectional, questionnaire-based anonymized survey screened 2500 parents of children with allergic ...
Akihiro Maeta, Yuri Takaoka, Atsuko Nakano, Yukiko Hiraguchi, Masaaki Hamada, Yutaka Takemura, Tomoko Kawakami, Ikuo Okafuji, Makoto Kameda, Kyoko Takahashi   +9 more
doaj   +1 more source

Hepatocellular carcinoma and multidrug resistance: Past, present and new challenges for therapy improvement [PDF]

, 2015
Hepatocellular carcinoma (HCC) is the most common malignancy of the liver and the third cause of cancer death worldwide. Chronic hepatitis due to HBV and HCV infection are two major risk factors for HCC worldwide.
Cuestas, María Luján, Mathet, Veronica Lidia, Oubiña, Jose Raul   +2 more
core   +1 more source

Food allergy oral immunotherapy

Journal of Food Allergy, 2020
Food allergy oral immunotherapy (OIT) has demonstrated efficacy in promoting clinically relevant immunomodulation that leads to desensitization (reduced reactivity while on OIT) in the majority of treated individuals; however, sustained unresponsiveness after OIT cessation for a specified interval has only been observed in a subset.
Sood, Amika K., Scurlock, Amy M.
openaire   +2 more sources

A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis [PDF]

, 2013
© Queen’s Printer and Controller of HMSO 2013Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing
Barton, P, Dretzke, J, Fry-Smith, A, Huissoon, A, Kaambwa, B, Meadows, A, Meads, C, Novielli, N   +7 more
core   +1 more source

Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals [PDF]

, 2014
Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic ...
Finocchiaro, Liliana Maria Elena, Glikin, Gerardo Claudio   +1 more
core   +4 more sources

Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy

Frontiers in Immunology, 2020
IgE-mediated food allergies are caused by adverse immunologic responses to food proteins. Allergic reactions may present locally in different tissues such as skin, gastrointestinal and respiratory tract and may result is systemic life-threatening ...
Ann-Marie Malby Schoos, Ann-Marie Malby Schoos, Dominique Bullens, Dominique Bullens, Bo Lund Chawes, Joana Costa, Liselot De Vlieger, Audrey DunnGalvin, Audrey DunnGalvin, Michelle M. Epstein, Johan Garssen, Johan Garssen, Christiane Hilger, Karen Knipping, Karen Knipping, Annette Kuehn, Dragan Mijakoski, Dragan Mijakoski, Daniel Munblit, Daniel Munblit, Nikita A. Nekliudov, Cevdet Ozdemir, Cevdet Ozdemir, Karine Patient, Diego Peroni, Sasho Stoleski, Sasho Stoleski, Eva Stylianou, Mirjana Tukalj, Mirjana Tukalj, Mirjana Tukalj, Kitty Verhoeckx, Mihaela Zidarn, Willem van de Veen, Willem van de Veen   +34 more
doaj   +1 more source

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition [PDF]

, 2014
Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage.
A Micheli, AB Castro-Junior, AM Faria, Barbara-ann Guinn, DJ Needham, Garrett Casey, Gerald C. O'Sullivan, H Nishikawa, HL Weiner, HL Weiner, HY Wang, J Larkin, J Murphy, John O. Larkin, L Chen, Maria C. Whelan, Mark Tangney, MC Whelan, MG O'Brien, P Castro-Sanchez, RB Nussenblatt, SA Collins, SD Khare, V Boncheva, Valli De Re, X Wang, Y Chen, Y Zhang   +27 more
core   +4 more sources