Results 291 to 300 of about 2,362,461 (350)

Sublingual and oral immunotherapy

Immunology and Allergy Clinics of North America, 2004
Sublingual immunotherapy (SLIT) is a viable alternative to the subcutaneous route for the treatment of respiratory allergy, whereas the pure oral route has been abandoned because of its lack of efficacy. The main distinctive feature of SLIT is its optimal safety profile, which has been demonstrated in adults and children.
CANONICA, GIORGIO, Compalati E, Fumagalli F, PASSALACQUA, GIOVANNI   +3 more
openaire   +2 more sources

Advances, practical implementation, and unmet needs regarding oral immunotherapy for food allergy.

Journal of Allergy and Clinical Immunology: In Practice, 2021
Treatment of food allergy is a rapidly changing landscape with arguably, the most significant advancement in recent years, the transition of oral immunotherapy (OIT) to clinical practice.
K. Perrett, Tina Sindher, P. Bégin, Josiah Shanks, A. Elizur   +4 more
semanticscholar   +1 more source

Egg oral immunotherapy

Current Opinion in Allergy & Clinical Immunology, 2012
Egg allergy is one of the most common food allergies of childhood and no interventional therapy is currently approved by the Food and Drug Administration. Much recent research has focused on the safety, efficacy, and mechanism of oral immunotherapy (OIT) as a disease-modifying treatment.Small pilot studies with varying protocol designs have shown egg ...
openaire   +2 more sources

Neutralizing IgG4 antibodies are a biomarker of sustained efficacy after peanut oral immunotherapy.

Journal of Allergy and Clinical Immunology
BACKGROUND Clinical efficacy of oral immunotherapy (OIT) has been associated with the induction of blocking antibodies, particularly those capable of disrupting IgE-allergen interactions.
Tarun Keswani, Nicole A. LaHood, Orlee Marini-Rapoport, Bijoya Karmakar, Léna Andrieux, Brian B Reese, S. L. Sneed, Lars C Pedersen, Geoffrey A. Mueller, Sarita U. Patil   +9 more
semanticscholar   +1 more source

Oral immunotherapy for food allergy

Current Allergy and Asthma Reports, 2009
Food allergy is an increasingly prevalent disorder with potentially life-threatening complications that requires life-altering changes in dietary habits and psychosocial interactions. The standard of care presently includes strict dietary elimination of the implicated allergen and ready access to injectable epinephrine; however, no active, definitive ...
Amy M, Scurlock, A Wesley, Burks, Stacie M, Jones   +2 more
openaire   +2 more sources

Oral Immunotherapy (OIT)

2020
Currently, there is no approved therapy for food allergies. Thus, treatment strategies are limited to avoidance of the allergic food and having emergency treatment available for reactions. An increasing amount of research into food allergy treatments has occurred in response to this void, with oral immunotherapy (OIT) being the most researched ...
Jay A. Lieberman, Julie Wang
openaire   +1 more source

Oral immunotherapy for peanut allergy

BMJ, 2010
A potentially important advance, but long term effectiveness and safety need to be ...
Aziz, Sheikh, Iris, Venderbosch, Ulugbek, Nurmatov   +2 more
openaire   +2 more sources

Oral Immunotherapy for Allergic Conjunctivitis

Cornea, 2014
Antigen-specific immunotherapy is expected to be a desirable treatment for allergic diseases. Currently, antigen-specific immunotherapy is performed by administering disease-causing antigens subcutaneously or sublingually. These approaches induce long-term remission in patients with allergic rhinitis or asthma.
Waka, Ishida, Ken, Fukuda, Yosuke, Harada, Hideo, Yagita, Atsuki, Fukushima   +4 more
openaire   +2 more sources

pH‐Responsive β‐Glucans‐Complexed mRNA in LNPs as an Oral Vaccine for Enhancing Cancer Immunotherapy

Advances in Materials
mRNA vaccines for cancer immunotherapy are commonly delivered using lipid nanoparticles (LNPs), which, when administered intravenously, may accumulate in the liver, potentially limiting their therapeutic efficacy.
Po-Kai Luo, Hui‐Min Ho, Min-Chun Chiang, Li‐An Chu, Ya-Han Chuang, Ping-Chiang Lyu, I-Chen Hu, Wan-An Chang, Sheng-Yao Peng, Jayachandran Jayakumar, Hsin-Lung Chen, Ming-Hsi Huang, Hsing‐Wen Sung   +12 more
semanticscholar   +1 more source

Oral immunotherapy for food allergy

Current Opinion in Pediatrics, 2010
Food allergy is a difficult clinical problem for which no disease-modifying therapy currently exists.The daily administration of graded allergen doses through oral immunotherapy (OIT) is one promising experimental approach to the development of a clinically available treatment.
Brian P, Vickery, Wesley, Burks
openaire   +2 more sources