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Oral Immunotherapy for Peanut Allergy
Annual Review of Medicine, 2016Peanut allergy is a common disease and the cause of severe, life-threatening allergic reactions and death. It is rarely outgrown; most pediatric patients carry the disease into adulthood. Peanut allergy poses a significant burden on the quality of life of sufferers and their families, which results mainly from the fear of accidental peanut ingestion ...
Katherine, Anagnostou, Andrew, Clark
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pH‐Responsive β‐Glucans‐Complexed mRNA in LNPs as an Oral Vaccine for Enhancing Cancer Immunotherapy
Advances in MaterialsmRNA vaccines for cancer immunotherapy are commonly delivered using lipid nanoparticles (LNPs), which, when administered intravenously, may accumulate in the liver, potentially limiting their therapeutic efficacy.
Po-Kai Luo +12 more
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Oral Immunotherapy for Food Allergy
Immunology and Allergy Clinics of North America, 2016Food allergy is a potentially life-threatening condition with no approved therapies, apart from avoidance and injectable epinephrine for acute allergic reactions. Oral immunotherapy (OIT) is an experimental treatment in which food-allergic patients consume gradually increasing quantities of the food to increase their threshold for allergic reaction ...
Allison J, Burbank +3 more
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Oral immunotherapy for food allergy
Current Allergy and Asthma Reports, 2008Current management of food allergy involves strict avoidance, education on recognizing and managing allergic reactions, and carrying an adrenaline autoinjector. This approach is burdensome and associated with reduced quality of life. Patients with food allergy would benefit greatly from a treatment that could achieve desensitization or long-term ...
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Oral Immunotherapy and Potential Treatment
2015The standardized therapeutic approach for food allergy is based on avoidance of allergens in foods. Oral immunotherapy (OIT) is a significant focus of food allergy research and appears to be effective in inducing desensitization. However, most patients receiving OIT have mild to moderate symptoms during the therapy, and it has not been clearly ...
Sakura, Sato +2 more
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Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology, 2022
Noriyuki Yanagida, Masaki Futamura
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Noriyuki Yanagida, Masaki Futamura
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Oral Immunotherapy: An Overview.
The Medical clinics of North America, 2023Oral immunotherapy (OIT) is an alternative treatment of IgE-mediated food allergy that has been shown to increase tolerance threshold to many of the top food allergens, although this effect may be dependent on age, dose, frequency, and duration.
Krista, Todoric, Sarah, Merrill
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First Oral Immunotherapy for Peanut Allergy
AJN, American Journal of Nursing, 2020Peanut (Arachis hypogaea) allergen powder-dnfp (Palforzia) is the first oral immunotherapy for children ages four to 17 years who have been diagnosed with a peanut allergy.Like subcutaneous forms of immunotherapy, Palforzia introduces the allergen in increasing doses and risks inducing allergic responses, including ...
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