Results 41 to 50 of about 2,166,017 (392)

A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis [PDF]

, 2013
© Queen’s Printer and Controller of HMSO 2013Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing
Barton, P, Dretzke, J, Fry-Smith, A, Huissoon, A, Kaambwa, B, Meadows, A, Meads, C, Novielli, N   +7 more
core   +1 more source

Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy

Frontiers in Immunology, 2020
IgE-mediated food allergies are caused by adverse immunologic responses to food proteins. Allergic reactions may present locally in different tissues such as skin, gastrointestinal and respiratory tract and may result is systemic life-threatening ...
Ann-Marie Malby Schoos, Ann-Marie Malby Schoos, Dominique Bullens, Dominique Bullens, Bo Lund Chawes, Joana Costa, Liselot De Vlieger, Audrey DunnGalvin, Audrey DunnGalvin, Michelle M. Epstein, Johan Garssen, Johan Garssen, Christiane Hilger, Karen Knipping, Karen Knipping, Annette Kuehn, Dragan Mijakoski, Dragan Mijakoski, Daniel Munblit, Daniel Munblit, Nikita A. Nekliudov, Cevdet Ozdemir, Cevdet Ozdemir, Karine Patient, Diego Peroni, Sasho Stoleski, Sasho Stoleski, Eva Stylianou, Mirjana Tukalj, Mirjana Tukalj, Mirjana Tukalj, Kitty Verhoeckx, Mihaela Zidarn, Willem van de Veen, Willem van de Veen   +34 more
doaj   +1 more source

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition [PDF]

, 2014
Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage.
A Micheli, AB Castro-Junior, AM Faria, Barbara-ann Guinn, DJ Needham, Garrett Casey, Gerald C. O'Sullivan, H Nishikawa, HL Weiner, HL Weiner, HY Wang, J Larkin, J Murphy, John O. Larkin, L Chen, Maria C. Whelan, Mark Tangney, MC Whelan, MG O'Brien, P Castro-Sanchez, RB Nussenblatt, SA Collins, SD Khare, V Boncheva, Valli De Re, X Wang, Y Chen, Y Zhang   +27 more
core   +4 more sources

Oral Immunotherapy for Food Allergies [PDF]

Annals of Nutrition and Metabolism, 2016
Oral immunotherapy (OIT) is a promising investigational therapy for food allergy. Clinical trials in peanut, milk, egg, and wheat allergy provide evidence that OIT can effectively desensitize a majority of individuals to a food allergen. While a portion of subjects demonstrate sustained unresponsiveness, the majority regain sensitivity with allergen ...
Elizabeth, Feuille, Anna, Nowak-Węgrzyn
openaire   +2 more sources

Oral Immunotherapy for Food-Allergic Children: A Pro-Con Debate

Frontiers in Immunology, 2021
The prevalence of food allergy has increased in recent years, especially in children. Allergen avoidance, and drugs in case of an allergic reaction, remains the standard of care in food allergy.
F. Mori, M. Giovannini, S. Barni, R. Jiménez‐Saiz, D. Munblit, Benedetta Biagioni, G. Liccioli, L. Sarti, L. Liotti, S. Ricci, E. Novembre, U. Sahiner, Ermanno Baldo, D. Caimmi   +13 more
semanticscholar   +1 more source

Oral Immunotherapy for Food Allergy [PDF]

Journal of Investigational Allergology and Clinical Immunology, 2017
Food allergy is a potentially life-threatening condition with no approved therapies apart from avoidance and injectable epinephrine for treatment of acute allergic reactions. Oral immunotherapy (OIT) is an experimental treatment in which patients consume gradually increasing quantities of the food to which they are allergic in an attempt to induce some
Deborah M Hussey, Freeland, Monali, Manohar, Sandra, Andorf, Benjamin D, Hobson, Wenming, Zhang, Kari C, Nadeau   +5 more
openaire   +5 more sources

Peanut allergy oral immunotherapy drives single-cell multi-omic changes in peanut-reactive T cells associated with sustained unresponsiveness. [PDF]

Nat Immunol
Han X, Skatova V, Mikelov A, Ji X, Hoh RA, Lee JY, Cao S, Seastedt H, Schuetz J, Fernandes A, Singhal A, Grubert F, DeKruyff RH, Maecker HT, Galli SJ, Manohar M, Chinthrajah RS, Kasowski MM, Boyd SD, Nadeau KC.   +19 more
europepmc   +3 more sources

Cochrane acute respiratory infections group's stakeholder engagement project identified systematic review priority areas [PDF]

, 2018
Objective: Cochrane acute respiratory infections (ARIs) group conducts systematic reviews of the evidence for treatment and prevention of ARIs. We report the results of a prioritization project, aiming to identify highest priority systematic review ...
Clark, Justin, Del Mar, Chris, Dooley, Liz, Jones, Ann, Jones, Mark, Scott, Anna Mae   +5 more
core   +1 more source

Peanut oral immunotherapy: current trends in clinical trials

Immunotherapy Advances, 2022
Immunotherapy for allergy has been practiced for over 100 years. Low-dose repeated exposure to specific allergen extracts over several months to years can successfully induce clinical tolerance in patients with allergy to insect venoms, pollen, house ...
S. Reinwald, J. Rolland, R. O'Hehir, M. V. van Zelm   +3 more
semanticscholar   +1 more source

Effect of Oral Immunotherapy on Nasal Blockage in Experimental Allergic Rhinitis

Journal of Pharmacological Sciences, 2005
We previously reported that when Japanese cedar pollen was prophylactically p.o. administered before a sensitization stage in a guinea-pig model of allergic rhinitis, pollen-induced nasal blockage was suppressed.
Takeshi Nabe, Kayoko Kubota, Tetsuya Terada, Hiroshi Takenaka, Shigekatsu Kohno   +4 more
doaj   +1 more source