Results 41 to 50 of about 138,961 (205)

Can the plasma PD-1 levels predict the presence and efficiency of tumor-infiltrating lymphocytes in patients with metastatic melanoma? [PDF]

, 2019
Background: The immune response in melanoma patients is locally affected by presence of tumor-infiltrating lymphocytes (TILs), generally divided into brisk, nonbrisk, and absent.
Badalamenti G., Bazan V., Fanale D., Fulfaro F., Incorvaia L., Iovanna J. L., Olive D., Rinaldi G., Russo A., Swayden M., Terruso L., Vincenzi B.   +11 more
core   +1 more source

The Anti-EMMPRIN Monoclonal Antibody hMR18-mAb Induces Tumor Dormancy and Inhibits the EMT Process in Human Carcinoma Cell Lines Co-Cultured with Macrophages

Biomedicines
Background: The epithelial-to-mesenchymal transition (EMT) process is necessary for metastasis as it enables tumor cells’ migration and invasion. In the remote organ, tumor cells can develop into metastatic lesions or arrest their proliferation and ...
Elina Simanovich, Felix Oyelami, Phillipp Brockmeyer, Michal A. Rahat   +3 more
doaj   +1 more source

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Adrian J. Thrasher, Arturo Sala, Chow, Croce, Dale, Daniel A. Morgenstern, Giorgia Santilli, Ikeda, Izabela Piotrowska, John Anderson, Katie Pearson, Marco D'Alicarnasso, Nourredine Himoudi, Olesya Chayka, Sandra Cantilena   +14 more
core   +2 more sources

Clinical and histopathological features of the first known case of glycogenic acanthosis resembling an isolated gingival tumour: A case report

Oral and Maxillofacial Surgery Cases
Glycogenic acanthosis is a common benign lesion of the oesophagus. However, extra-oesophageal localisations in the larynx and oral mucosa in the form of white, papular or plaque-like lesions are possible.
Svyat Strokov, Anne-Laure Ejeil, Hélène Raybaud, Christine Voha, Sophie-Myriam Dridi   +4 more
doaj   +1 more source

Alopecia areata: a multifactorial autoimmune condition [PDF]

, 2019
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is clinically characterised by small patches of baldness on the scalp and/or around the body. It can later progress to total loss of scalp hair (Alopecia totalis) and/
Butcher, John P., Henriquez, Fiona L., Reid, Stuart, Simakou, Teontor   +3 more
core   +1 more source

Evaluation of peripheral basophil activation during exercise provocation test for desensitized patients

Frontiers in Allergy, 2023
Some food allergic patients who have undergone oral immunotherapy develop exercise-induced allergic reactions on desensitization (EIARDs). This study investigated basophil activation status during the exercise provocation test (EPT) performed to diagnose
Jun Kunizaki, Jun Kunizaki, Shiro Sugiura, Akira Sakai, Akira Sakai, Miyuki Teshigawara, Atsushi Makino, Yoshihiro Takasato, Teruaki Matsui, Yasuto Kondo, Komei Ito   +10 more
doaj   +1 more source

Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer. [PDF]

, 2017
INTRODUCTION: Colorectal cancer remains the second leading cause of cancer death in the United States, and new strategies to prevent, detect, and treat the disease are needed.
Aka, Allison A., Pattison, Amanda M., Rappaport, Jeff A., Sato, Takami, Snook, Adam E., Waldman, Scott A.   +5 more
core   +2 more sources

Bypassing the build-up phase for oral immunotherapy in shrimp-allergic children

World Allergy Organization Journal
Background: Oral immunotherapy is an effective treatment for food allergies; however, its use in clinical practice is limited by resources and lack of standardized protocols for foods other than peanut.
Ann-Marie M. Schoos, MD, PhD, DMSc, Edmond S. Chan, MD, Tiffany Wong, MD, Stephanie C. Erdle, MD, Alanna Chomyn, MD, Lianne Soller, PhD, Raymond Mak, MD   +6 more
doaj   +1 more source

Food-specific sublingual immunotherapy is well tolerated and safe in healthy dogs : a blind, randomized, placebo-controlled study [PDF]

, 2017
Background: Food allergies are increasing in prevalence but no treatment strategies are currently available to cure dogs with food allergy. Over the past decade, experimental food allergen-specific sublingual immunotherapy (FA-SLIT) has emerged as a ...
Cox, Eric, Hesta, Myriam, Maina, Elisa, Pelst, Michael   +3 more
core   +2 more sources

Peanut allergy: Beyond the oral immunotherapy plateau

Clinical and Translational Allergy, 2021
Background There are a lack of disease‐modifying treatments for peanut allergy, which is lifelong in most instances. Oral immunotherapy has remained at the forefront of prospective treatments, though its efficacy is consistently undermined by the risk of
Kelly Bruton, Paul Spill, Derek K. Chu, Susan Waserman, Manel Jordana   +4 more
doaj   +1 more source