Results 91 to 100 of about 1,639,084 (252)

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Educational strategies designed to promote primary and secondary prevention of melanoma / Rona M. Mackie and Natale Cascinelli for and on behalf of the World Health Organization Melanoma Programme

, 1992
31 ...
World Health Organization. Melanoma Programme, Mackie, Rona M, Cascinelli, Natale   +2 more
core  

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis [PDF]

, 2013
The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated.
Graf, M, Mesher, D, Francesca Moretti, Chiorino, G, A. Chikh, Costanzo, A, M. Graf, D. Bergamaschi, Leigh, IM, Cerio, R, Maria Scatolini, Chong, SLP, C. M. Proby, Anissa Chikh, Antonio Costanzo, Matin, RN, Moretti, F, COSTANZO, ANTONIO, Charlotte M. Proby, Valentina Senatore, C. A. Harwood, Senatore, V, I. M. Leigh, D. Mesher, Harwood, CA, Catherine A. Harwood, R. N. Matin, Stephanie Law Pak Chong, Paolo Sanza’, Rino Cerio, R. Cerio, Bergamaschi, D, David Mesher, P. Sanza', M. Scatolini, Irene M. Leigh, S. L. Pak, Rubeta N. Matin, Proby, CM, V. Senatore, Daniele Bergamaschi, F. Moretti, Chikh, A, Sanza', P, Scatolini, M, Giovanna Chiorino, G. Chiorino, Manuela Graf   +47 more
core   +1 more source

North American Delphi Consensus Study on Sinonasal Malignancy Survivorship Care

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Survival for patients with sinonasal cancers has improved over the past decades, but there are no dedicated survivorship guidelines for this cohort. Objective To understand experts’ priorities and perspectives on key survivorship tenets (surveillance, second tumor screening, toxicity, and symptom management).
Matheus Sewastjanow‐Silva, Samagra Jain, Rita Snyder, Erin L. McKean, Ralph Abi Hachem, Nithin D. Adappa, J. Ken Byrd, Ricardo L. Carrau, Marc A. Cohen, Ivan H. El‐Sayed, Mathew N. Geltzeiler, Ehab Y. Hanna, Edward C. Kuan, Nyall R. London Jr., Zoukaa B. Sargi, Carl H. Snyderman, Marilene B. Wang, Ian J. Witterick, Shirley Y. Su   +18 more
wiley   +1 more source

Oral malignant melanoma: A case report with review of literature

Contemporary Clinical Dentistry, 2014
Oral mucosal melanoma is a rare malignancy with the tendency to metastasize and locally invade tissues more readily than other malignant tumor of the oral cavity.
T Manigandan, G Vikram Sagar, A Amudhan, V T Hemalatha, N Aravinda Babu   +4 more
doaj   +1 more source

Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells. [PDF]

, 2014
BACKGROUND: The importance of the genetic background of cancer cells for the individual susceptibility to cancer treatments is increasingly apparent.
Ferguson, J., Claudia Wellbrock, Erice, O., Margison, G.P., Goicoechea, I., Geoffrey P Margison, Margison, Geoffrey P, Wellbrock, C., Wellbrock, Claudia, Jennnifer Ferguson, Arozarena, Imanol, Goicoechea, Ibai, Imanol Arozarena, Ferguson, Jennnifer, Erice, Oihane, Oihane Erice, Ibai Goicoechea   +16 more
core   +1 more source

Molecular mechanism of Xanthotoxol against gastric cancer: A comprehensive study integrating network pharmacology, computer simulations, and experimental validation

Animal Models and Experimental Medicine, EarlyView.
Our study systematically explored the anti‐gastric cancer (GC) mechanism of Xanthotoxol (Xan), a natural active phytochemical, using an integrated strategy of network pharmacology, molecular simulation, and experimental validation. First, we identified 39 hub genes associated with gastric cancer using weighted gene co‐expression network analysis (WGCNA)
Yi Yang, Yu‐Hua Du, Chuang Song, Lan‐Nv Ma, Lin Luo, De‐Xu Xu, Xiao‐Yan Ma, Zi‐Ying Zhou, Yi Nan, Yi Yang, Ling Yuan   +10 more
wiley   +1 more source

Risk of Cancer According to Duration of Targeted Therapy Exposure in Spondyloarthritis: A Nationwide Cohort Study From the French Health Insurance Database

Arthritis &Rheumatology, EarlyView.
Objective To assess the association between duration of targeted therapy exposure and cancer risk in patients with spondyloarthritis (SpA), including those with psoriatic arthritis, axial SpA, and other subtypes. Methods This nationwide cohort study used the French health insurance database to identify adults with SpA initiating a targeted therapy ...
Karine Tankovic, Pascal Claudepierre, Tat Thang Vo, Tran Trong Khoi Le, Siham Iggui, Laetitia Penso, Emilie Sbidian, Laura Pina Vegas   +7 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Oral mucosal melanoma: conservative treatment including laser surgery.

, 2011
Objective: To discuss the convenience of laser surgery as optimal treatment for melanoma of the oral mucosa.Patients and methods: A retrospective evaluation of four patients with primary oral melanomas treated at a single Cancer Institution in Mexico ...
Campos-Ramos, E., Mosqueda-Taylor, A., Luna-Ortiz, K., Pasche, P.   +3 more
core   +1 more source