Results 221 to 230 of about 1,639,084 (252)

Current state of medical care for patients with mycosis fungoides and Sézary syndrome at a German university hospital – a cross‐sectional study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Studies on the state of medical care for patients with cutaneous T‐cell lymphoma (CTCL) are limited. To date, only secondary data analyses are available for Germany. Patients and Methods Cross‐sectional study conducted over a one‐year recruitment period (01 March 2024 to 28 February 2025) in the dermatological department of a German ...
Inga Hansen‐Abeck, Larissa Kölln, Finn Abeck, Glenn Geidel, Stefan W. Schneider, Nina Booken   +5 more
wiley   +1 more source

Severe neck stiffness in a 20‐year‐old gelding with cytological findings suggestive of cervical vertebral neoplasm

Equine Veterinary Education, EarlyView.
Summary A 20‐year‐old warmblood gelding was referred for the evaluation of severe cervical stiffness and pain. Radiographic examination revealed marked arthropathy of the C3–C4 articular processes, with severe remodelling and narrowing of the C3–C4 intervertebral space.
F. Bonaspetti, E. Porzio, M. Sforna, A. Mascioni, F. Beccati   +4 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Clinical Outcomes of Gradual Corticosteroid Tapering for Immune Checkpoint Inhibitor‐Induced Liver Injury

Hepatology Research, EarlyView.
Patients with severe ICI‐induced liver injury are commonly treated with corticosteroids, but the optimal tapering strategy remains uncertain. In this study, a gradual corticosteroid tapering strategy based partly on Japanese clinical practice for autoimmune hepatitis was associated with a low rate of relapse and enabled many patients to safely resume ...
Naoto Soma, Yoshihito Uchida, Kayoko Sugawara, Masamitsu Nakao, Nobuaki Nakayama, Yukinori Imai, Suguru Mizuno, Satoshi Mochida   +7 more
wiley   +1 more source

Rethinking Dental Hygiene Practice: Home‐Based Oral Health Care for Older Adults With Complex Care Needs

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background As populations age, increasing numbers of older adults live with multimorbidity, frailty and functional decline, making it difficult or impossible for many older adults to access traditional dental clinics. Despite this growing need, oral health care in home‐care settings remains underdeveloped, with limited guidelines, resources ...
Mersiha Velic, Jessica Persson Kylén
wiley   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Doing It All or Doing It Best: An Umbrella Review of the Effectiveness of Specialist Cancer Nurse‐Led Care

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To investigate the effectiveness, including economic outcomes, of specialist cancer nurse‐led interventions. Design A systematic umbrella review, reported in accordance with PRISMA guidelines. Methods Systematically conducted reviews reporting any effectiveness or cost‐effectiveness outcomes published between January 2014 and June 2025 ...
Carla Thamm, Elise Button, Megan Crichton, Andreas Charalambous, Juliana Christina, Murray R. Turner, Joe Wing Pun, Fiona Crawford‐Williams, Olivia Cook, Jane Mahony, Kerry Patford, Natasha Doherty, Catherine Paterson, Raymond J. Chan   +13 more
wiley   +1 more source

HPV125‐induced generalized verrucosis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven Niklas Burmann, Ulrike Wieland, Finja Schweitzer, Frank Oellig, Mihael Skerlev, David Chromy, Alexander Kreuter, Steffi Silling   +7 more
wiley   +1 more source

Immune effector cell‐associated neurotoxicity syndrome (ICANS) during tebentafusp in metastatic uveal melanoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Laura Schreieder, Laura Jockel, Veronika Zenderowski, Ralf A. Linker, Sebastian Haferkamp, Elisabeth Bumes, Peter Hau, Konstantin Drexler   +7 more
wiley   +1 more source