Results 91 to 100 of about 1,597,894 (263)

The performance of an oral microbiome biomarker panel in predicting oral cavity and oropharyngeal cancers

, 2018
The oral microbiome can play a role in the instigation and progression of oral diseases that can manifest into other systemic conditions. These associations encourage the exploration of oral dysbiosis leading to the pathogenesis of cancers. In this study,
Lim, Yenkai, Yenkai Lim, Naoki Fukuma, Mark Morrison, Chamindie Punyadeera, Totsika, Makrina, Kenny, Liz, Punyadeera, Chamindie, Makrina Totsika, Liz Kenny, Fukuma, Naoki, Morrison, Mark   +11 more
core   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +2 more sources

IgG In Saliva, GCF, and Serum in Young Patients With Grade C Molar Incisor Pattern Periodontitis

Clinical and Experimental Dental Research
Objective This cross‐sectional study aimed to investigate immunoglobulin G levels in saliva, gingival crevicular fluid, and serum samples from young patients with grade C molar incisor pattern periodontitis (C/MIP) and age‐matched periodontitis‐free ...
Meaad M. Alamri, Gordon Proctor, Luigi Nibali   +2 more
doaj   +1 more source

Marsupial oral cavity microbiome [PDF]

, 2015
Published: 6 March 2015The oral microbiome of humans and animals will cause oral disease within their lifetimes and include a large number of endogenous cariogenic, periodontal and other opportunistic pathogens.
Bird, P.S., Blackall, Linda L., Bird, Philip S., Boardman, Wayne S. J., Blackall, L.L., Trott, D.J., Boardman, W.S.J., Trott, Darren J.   +7 more
core   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Efficacy of a mouthwash containing ε-poly-L-lysine, funme peptides and domiphen in reducing halitosis and supragingival plaque: a randomized clinical trial

BMC Oral Health
Objective To evaluate the antibacterial effectiveness of a combination of ε-poly-L-lysine (ε-PL), funme peptide (FP) as well as domiphen against oral pathogens, and assess the efficacy of a BOP® mouthwash supplemented with this combination in reducing ...
Song Shen, Xu Liu, Jun Huang, Yi Sun, Bin Liu, Wenzhu Song, Lei Meng, Mi Du, Qiang Feng   +8 more
doaj   +1 more source

Impact of polyols on Oral microbiome of Estonian schoolchildren [PDF]

, 2019
Background Oral microbiome has significant impact on both oral and general health. Polyols have been promoted as sugar substitutes in prevention of oral diseases.
Saag, Mare, Nõlvak, Hiie, Riina Runnel, Truu, Jaak, Kauko Mäkinen, Mäkinen, Pirkko-Liisa, Jana Olak, Reet Mändar, Krjutškov, Kaarel, Oopkaup, Kristjan, Mäkinen, Kauko, Jens-Konrad Preem, Preem, Jens-Konrad, Honkala, Eino, Tero Vahlberg, Peter de Cock, Joan Vermeiren, Bosscher, Douwina, Vahlberg, Tero, Mare Saag, Nõmmela, Rita, Jaak Truu, Olak, Jaana, Honkala, Sisko, Mändar, Reet, Rita Nõmmela, Jelena Štšepetova, Eino Honkala, Pirkko-Liisa Mäkinen, Sisko Honkala, de Cock, Peter, Hiie Nõlvak, Kaarel Krjutškov, Vermeiren, Joan, Runnel, Riina, Kristjan Oopkaup, Douwina Bosscher, Štšepetova, Jelena   +37 more
core   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source