Results 91 to 100 of about 1,752,430 (254)

Breast Milk Microbiota and Its Effects on the Development of Oral Microbiota

, 2021
ÖZET Anne sütünün, içerdiği immünglobulinler, biyoaktif proteinler ve oligosakkaritler ile bebeğin büyüme ve gelişiminde önemli rol oynadığı bilinmektedir.
Sepet, Elif, Pınar Erdem, Arzu, Parlak, Büşra   +2 more
core  

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

The role of oral microbiota in digestive system diseases: current advances and perspectives

Journal of Oral Microbiology
The oral microbiota is intimately linked to human health and various disease states. With the advent of the Human Microbiome Project, our comprehension of the oral microbiota has substantially improved.
Yaqi Li, Yiping Xin, Wenlu Zong, Xiaoyu Li   +3 more
doaj   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

Advanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park, Yeongkag Kwon, Yeonjin Lim, Jeong Woo Park, Hyun Jung Ji, Dongwook Lee, Jueun Lee, Sung‐Ho Yun, Sungho Jeong, Ho Seong Seo, Kun Cho, Cheol‐Heui Yun, Ok‐Jin Park, Seung Hyun Han   +13 more
wiley   +1 more source

Fact-finding survey: oral microbiota activity and use of probiotics in the dental field

, 2023
reservedIl microbiota umano rappresenta l'insieme dei microorganismi (batteri, funghi, archeobatteri, protozoi, e virus) che vivono in simbiosi con il corpo umano, sia in condizioni fisiologiche che, talvolta, in situazioni patologiche.
SIGNORI, CAMILLA
core  

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Modulation of oral and faecal microbiota by cheese: Relationships with sweet taste sensitivity in rat.

Journal of Functional Foods
The oral cavity contains a large community of microorganisms known as the oral microbiota. This oral microbiota can be modulated by the consumption of fermented food (FF) in rat but the impact of FF consumption on the microbiota (oral and faecal) of ...
M. Ibarlucea-Jerez, M. Monnoye, H. Brignot, P. Gérard, H. Licandro, E. Neyraud   +5 more
doaj   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Postmenopausal osteoporosis increases periodontal inflammation and the pathogenicity of the oral microbiota in a rat model

Journal of Oral Microbiology
Objectives This study aims to explore the mechanisms of the detrimental effects of postmenopausal osteoporosis (PMO) on periodontitis.Methods An ovariectomized (OVX) rat model was established to investigate the effects of PMO on alveolar bone homeostasis
Miao Lu, Yanan Zhang, Yang Zhang, Xulei Yuan, Tingwei Zhang, Jinlin Song   +5 more
doaj   +1 more source