Results 61 to 70 of about 16,042 (257)

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

Tuberculosis and gender: exploring the patterns in a case control study in Malawi. [PDF]

, 2004
BACKGROUND: In many populations there is an excess of tuberculosis in young women and older men. We explored possible explanations for these patterns, concentrating on human immunodeficiency virus (HIV) status, pregnancy, smoking, cooking smoke exposure,
Crampin, AC, Fine, PEM, Floyd, S, Glynn, JR, Malema, SS, Mwaungulu, FD, Mwinuka, VK, Ngwira, BMM, Warndorff, DK   +8 more
core  

A Pseudovirus‐Based Method for the Simultaneous Quantitation of Neutralization Antibodies Against All Three Poliovirus Serotypes

MedComm, Volume 6, Issue 12, December 2025.
By optimizing P1 expression, sensitive cell selection, and plasmid transfection ratios, we produced a high‐titer poliovirus pseudovirus. Based on high‐titer pseudovirus encoding distinct fluorophores (E2, eGFP, and RFP), we developed a tri‐color pseudovirus‐based neutralization assay (PBNA) for the simultaneous quantification of neutralizing antibodies
Meiyan Liu, Yuanling Yu, Yadong Li, Zexin Tao, Lan Huang, Xi Wu, Yong Zhang, Shuangli Zhu, Qiang Sun, Tianjiao Ji, Dongyan Wang, Ziteng Liang, Shuo Liu, Meina Cai, Yimeng An, Jierui Li, Weijin Huang, Guoyang Liao, Li Yi, Lei Ma, Li Zhang, Youchun Wang   +21 more
wiley   +1 more source

Role of Serial Polio Seroprevalence Studies in Guiding Implementation of the Polio Eradication Initiative in Kano, Nigeria: 2011-2014. [PDF]

, 2016
BACKGROUND: Nigeria was one of 3 polio-endemic countries before it was de-listed in September 2015 by the World Health Organization, following interruption of transmission of the poliovirus. During 2011-2014, Nigeria conducted serial polio seroprevalence
Abdullahi Walla, Ado J. G. Muhammad, Amina Ahmad-Shehu, Bashir Abba, Centers for Disease Control and Prevention, Harish Verma, Kebba Touray, Kehinde TemilolaOluwa Craig, Marina Takane, Olen, Pascal Mkanda, Peter Nsubuga, Richard Banda, Roland W. Sutter, Rui G. Vaz, Sisay G. Tegegne, Ticha Johnson, World Health Organization, Yared G. Yehualashet, Zubairu Iliyasu   +19 more
core   +1 more source

Crosstalk Between Cancer‐Associated Fibroblasts and Immune Cells: Mechanisms and Therapeutic Implications

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Cancer‐associated fibroblasts (CAFs) are widely engaged in tumor progression in the tumor microenvironment. CAFs interact actively with immunocytes including tumor‐associated macrophages, T cells, neutrophils, and NK cells in a positive‐feedback loop to sculpt tumor immune microenvironment and participate in tumor activities and antitumor therapy ...
Ya Li, Xingpeng Di, Jiawei Chen, Jingwen Wei, Tianyue Li, Kunjie Wang, Banghua Liao, Deyi Luo   +7 more
wiley   +1 more source

An Unusual Case of Vaccine-Associated Paralytic Poliomyelitis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2014
The present article reports a case involving an immunocompetent, previously well child who, despite two previous doses of inactivated poliovirus vaccine, developed severe flaccid paralysis consistent with polio after receiving oral polio vaccine.
S Desai, T Diener, BJ-K Tan, NJ Lowry, C Talukdar, WM Chrusch, S Wiebe   +6 more
doaj   +1 more source

Establishment of Realtime RT-PCR Assay to Detect Polio Virus in the Acute Flaccid Paralysis Laboratory Surveillance [PDF]

, 2016
Background: The last indigenous polio was detected in 1995 but the threat of wild type polio viruses and themutation of Oral Polio Vaccine into Vaccine-Derived Poliovirus still continue.
Setiawaty, V. (Vivi), Susanti, N. (Nike)
core   +2 more sources

The microbiome in cancer

iMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin, Minying Xiong, Aimin Jiang, Lihaoyun Huang, Hank Z. H. Wong, Suyin Feng, Chunyan Zhang, Yu Li, Li Chen, Hao Chi, Pengpeng Zhang, Bicheng Ye, Hengguo Zhang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Junyi Shen, Kailai Li, Wentao Xu, Haoxuan Ying, Cangang Zhang, Dongqiang Zeng, Jindong Xie, Xinpei Deng, Qi Wang, Jianying Xu, Wenjie Shi, Chang Qi, Chunrun Qu, Xufeng Huang, András Hajdu, Chaoqun Li, Changmin Peng, Xuanye Cao, Guangsheng Pei, Lin Zhang, Yujia Huo, Jiabao Xu, Antonino Glaviano, Attila Gábor Szöllősi, Sicheng Bian, Zhengrui Li, Hailin Tang, Bufu Tang, Zaoqu Liu, Jian Zhang, Kai Miao, Quan Cheng, Ting Wei, Shuofeng Yuan, Peng Luo   +50 more
wiley   +1 more source

Trends and measurement of HIV prevalence in northern Malawi.

, 2003
BACKGROUND: Most data on HIV prevalence in Malawi come from antenatal clinic (ANC) surveillance and are, therefore, subject to bias. OBJECTIVES: HIV prevalence and risk factors were measured using population-based data to assess the accuracy of ANC ...
Crampin, Amelia C, Fine, Paul E, Glynn, Judith R, Mwaungulu, Frank D, Ngwira, Bagrey M, Pönnighaus, Jörg M, Warndorff, David K   +6 more
core   +1 more source

From regional pulse vaccination to global disease eradication: insights from a mathematical model of Poliomyelitis [PDF]

, 2014
Mass-vaccination campaigns are an important strategy in the global fight against poliomyelitis and measles. The large-scale logistics required for these mass immunisation campaigns magnifies the need for research into the effectiveness and optimal ...
AJ Terry, AL Lloyd, B Alyward, B Shulgin, Cameron J. Browne, CC Chicone, CJ Browne, DD Bainov, DD Bainov, DD Bainov, DJD Earn, DM Morens, HR Thieme, J Burton, J Liu, JM Heffernan, KR Yameogo, L Bourouiba, LS Liebovitch, Lydia Bourouiba, M Kirkilionis, ME Birmingham, N Bacaer, N Bacaer, N Bacaër, P Driessche van den, PEM Fine, R Breban, Robert J. Smith, S Zipursky, V Lakshmikantham, W Wang, X Meng, X-Q Zhao, Y Xiao, YP Yang, Z Agur   +36 more
core   +2 more sources