Results 211 to 220 of about 103,250 (300)

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang   +5 more
wiley   +1 more source

Preclinical Efficacy and Safety Evaluation of a Novel Controlled‐Expansion ePTFE‐Covered TIPS Stent in a Swine Model

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
This preclinical study evaluated a novel controlled‐expansion expanded polytetrafluoroethylene (ePTFE)‐covered transjugular intrahepatic portosystemic shunt (TIPS) stent in 11 swine, demonstrating 100% technical success, excellent deployability, and durable 6‐month angiographic patency without thrombosis, migration, fracture, or device‐related toxicity.
Yi Xiang   +15 more
wiley   +1 more source

Biomimetic Multifinger Tactile Sensing and Contact‐Regulated Palpation for Autonomous Breast Tumor Localization

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Early detection of breast abnormalities remains challenging: manual palpation is subjective and operator‐dependent, while imaging modalities may miss small or subtle stiffness anomalies. This paper presents a biomimetic multifinger robotic palpation approach intended to support early breast‐cancer screening and follow‐up assessment as a proof ...
Kai Cheng   +7 more
wiley   +1 more source

Epistemic Objects and Tools on the School Grounds: Addressing Plant Blindness and Knowledge Construction

open access: yesScience Education, EarlyView.
ABSTRACT Plants mediate the supply of energy and matter for all animals, including human beings yet we are faced with “plant blindness” whereby we pay limited attention to and accord little value to plants. Plant blindness is evident in school curricula whereby students have limited opportunities to learn about plants.
Maurice M. W. Cheng, Bronwen Cowie
wiley   +1 more source

Objective sleep parameters and diurnal blood pressure in concurrent hypertension and type 2 diabetes

open access: yesSleep Research, EarlyView.
Abstract Background Hypertension is a primary cardiovascular complication in type 2 diabetes associated with increased morbidity and mortality. Ambulatory blood pressure monitoring (ABPM) is essential for capturing circadian BP variation, which is closely influenced by sleep. Methods Twenty patients (63.75 ± 4.44 years old, 40% female, duration of T2D:
Yan Zhao   +6 more
wiley   +1 more source

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

open access: yesSmall, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang   +16 more
wiley   +1 more source

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