Results 51 to 60 of about 103,250 (300)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Oral reading: practices and purposes in secondary classrooms [PDF]

, 2018
PURPOSE This paper aims to investigate teacher-initiated whole-group oral reading practices in two ninth-grade reading intervention classrooms and how teachers understood the purposes of those practices.
Brooks, Maneka Deanna, Frankel, Katherine K.   +1 more
core   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

Advanced Healthcare Materials, EarlyView.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao, Yi Zhu, Yusheng Wang, Janene M. Pierce, Jeffrey J. Tosoian, Xiaoguang Dong   +5 more
wiley   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Early oral language precursors of different types of reading difficulties in a consistent orthography

Frontiers in Education, 2022
The present longitudinal study examined whether early oral language skills of Greek-speaking children assessed in grade 1 can predict the type of reading difficulties (RD) in grade 2. Sixty-six typically developing (TD) children and eighty-seven children
Ioannis Grigorakis, Apostolos Kargiotidis, Angeliki Mouzaki, George Manolitsis   +3 more
doaj   +1 more source

Programa "Leitores do futuro" : automodelagem e leitura assistida na promoção da fluência na leitura oral [PDF]

, 2012
Tese de mestrado, Psicologia (Secção de Psicologia da Educação e da Orientação), Universidade de Lisboa, Faculdade de Psicologia, 2012A fluência na leitura oral constitui uma componente crítica da leitura proficiente, uma vez que contribui para a ...
Agostinho, Ana Lúcia Correia
core  

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

10-year-olds reading for meaning? A study of Sesotho Grade 4 learners’ foundational reading skills

South African Journal of Childhood Education
Background: South Africa’s PIRLS 2021 outcomes revealed that learners struggle with comprehension. The reasons for poor reading need to be identified and addressed to stem this challenge.
Maria K. Vaz
doaj   +1 more source

Identification of struggling readers or at risk of reading difficulties with one-minute fluency measures

Psicologia: Reflexão e Crítica, 2021
Background To identify readers who are struggling or at risk of reading difficulties, reference standards in oral reading fluency (ORF) are used to conduct an assessment that is based on a widely reported method known as curriculum-based measurement (CBM)
Maíra Anelli Martins, Simone Aparecida Capellini   +1 more
doaj   +1 more source

Monitoring oral reading fluency in elementary school I [PDF]

, 2023
Assessment measures of oral reading fluency can be applied by teachers or education professionals and help to provide an overview of the academic development in reading of each student; and when these simple measures are systematically applied over time, they can be used to track a student's possible difficulties.
Anelli Martins, Maíra, Del Bianco, Noemi, D’Angelo, Ilaria, Giaconi, Catia, Aparecida Capellini, Simone   +4 more
openaire   +2 more sources