Results 91 to 100 of about 257,176 (353)
Rabies elimination research: juxtaposing optimism, pragmatism and realism [PDF]
, 2017 More than 100 years of research has now been conducted into the prevention, control and elimination of rabies with safe and highly efficacious vaccines developed for use in human and animal populations. Domestic dogs are a major reservoir for rabies, and
Bögel K +13 more
core +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Tuberculosis and gender: exploring the patterns in a case control study in Malawi. [PDF]
, 2004 BACKGROUND: In many populations there is an excess of tuberculosis in young women and older men. We explored possible explanations for these patterns, concentrating on human immunodeficiency virus (HIV) status, pregnancy, smoking, cooking smoke exposure,
Crampin, AC +8 more
core
Reducing Campylobacter jejuni colonization in broiler chickens by in-feed supplementation with hyperimmune egg yolk antibodies [PDF]
, 2019 Campylobacter infections sourced mainly to poultry products, are the most important bacterial foodborne zoonoses worldwide. No effective measures to control these infections in broiler production exist to date.
Canessa, Stefano +8 more
core +1 more source
Rapid emergence and transmission of virulence-associated mutations in the oral poliovirus vaccine following vaccination campaigns [PDF]
, 2023 Katharine S. Walter +6 more
openalex +1 more source
Advanced Science, EarlyView.A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2015 Tuberculosis has great public health impact with high rates of mortality and the only prophylactic measure for it is the Mycobacterium bovisbacillus Calmette-Guérin (BCG) vaccine.
Periela da Silva Sousa-Vasconcelos +3 more
doaj +1 more source
Vaccines in Current Culture: The HPV Vaccine Controversy [PDF]
, 2020 The use of vaccinations has drastically decreased mortality and morbidity rates related to infectious disease and has become an intrinsic part of modern health care.
Johnston, Alyssa
core +1 more source
Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]
, 2016 BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P +6 more
core +3 more sources
Advanced Science, EarlyView.ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen +12 more
wiley +1 more source