Results 81 to 90 of about 341,025 (330)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Acta Societatis Botanicorum Poloniae, 2014 The feature of the orange colour of young seedlings, which appeared in inbred generation S2 of a short straw form of winter rye cultivated in Jeleniec is described.
Helena Kubicka +3 more
doaj +1 more source
Morphological character evolution of Amorphophallus (Araceae) based on a combined phylogenetic analysis of trnL, rbcL, and LEAFY second intron sequences [PDF]
, 2010 Sequences of three different genes in 69 taxa of Amorphophallus were combined to reconstruct the molecular phylogeny of this species-rich Aroid genus.
Eurlings, M.C.M. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
DUS characterization of muskmelon (Cucumis melo) varieties
The Indian Journal of Agricultural Sciences, 2015 The present study was carried out for morphological characterization of twelve reference varieties of muskmelon (Cucumis melo L.) collected from ICAR institutes and SAUs to validate DUS testing guidelines using plant descriptors adopted from the DUS ...
B R CHOUDHARY +3 more
doaj +1 more source
A novel three-colour fluorescence in situ hybridization approach for the detection of t(7;12)(q36;p13) in acute myeloid leukaemia reveals new cryptic three way translocation t(7;12;16) [PDF]
, 2013 © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).The t(7;12)(q36;p13 ...
Abdulbasit Naiel +14 more
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Revisiting the Andean butterfly Eryphanis zolvizora group (Lepidoptera, Nymphalidae) : one or several species? [PDF]
, 2014 Eryphanis zolvizora (Hewitson, 1877) is a rare Andean endemic butterfly, described from Bolivia, which has been historically classified either as a unique species, or as part of a group of three allopatric species from Bolivia, Ecuador and Colombia.
Blandini, Patrick +5 more
core +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Innovation and Entrepreneurship: A Colour Economy Glance [PDF]
SHS Web of ConferencesThis article introduces the topic of the Colour Economy as a set of new economic paradigms that seek to respond to global challenges such as sustainability, technological transformation and social inclusion.
Estrada Salvador +4 more
doaj +1 more source