Results 81 to 90 of about 318,817 (173)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Orbit Determination via a Deeply- Coupled UKF/GNSS Filter [PDF]

فصلنامه علوم و فناوری فضایی, 2016
This paper is dedicated to determining the orbit of a satellite by using Unscented Kalman Filter (UKF), in which, a GNSS is used as the observation sensor.
MohammadAli Amiri Atashgah, Hamid Gazerpour, seyed Amirreza Roghangir   +2 more
doaj  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Summary of Lunar Constellation Navigation and Orbit Determination Technology

Aerospace
The Moon is the closest celestial body to the Earth. Its rich unique resources are an important supplement to the Earth’s resources and have a profound impact on the sustainable development of human society.
Xiao Zhang, Zhaowei Sun, Xiao Chen, Linxin Pan, Yubin Zhong   +4 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Constraining Schwarzschild Models with Orbit Classifications [PDF]

arXiv
A simple orbit classification constraint extension to stellar dynamical modeling using Schwarzschild's method is demonstrated. The classification scheme used is the existing `orbit circularity' scheme (lambda_z) where orbits are split into four groups - hot, warm, cold and counter rotating orbits. Other schemes which can be related to the orbit weights
arxiv  

The Connection between the Quantum Frequency of Radiation and Frequencies of Circling of the Electron in Atom of Hydrogen [PDF]

arXiv, 2002
The connection between the quantum frequency of radiation by the transition of the electron from orbit n to orbit k and frequencies of circling of electron in these orbits for the atom of hydrogen is determined.
arxiv  

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

Molecular Oncology, EarlyView.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler, Emily Brieger, Tom Brandstätter, Elisa Hörterer, Ulrich Wilk, Jana Pöhmerer, Anna Jötten, Philipp Paulitschke, Chase P. Broedersz, Stefan Zahler, Joachim O. Rädler, Ernst Wagner, Andreas Roidl   +12 more
wiley   +1 more source

Overview on Space-Based Optical Orbit Determination Method Employed for Space Situational Awareness: From Theory to Application

Photonics
Leveraging space-based optical platforms for space debris and defunct spacecraft detection presents several advantages, including a wide detection range, immunity to cloud cover, and the ability to maintain continuous surveillance on space targets.
Zhe Zhang, Gaopeng Zhang, Jianzhong Cao, Cheng Li, Weining Chen, Xin Ning, Zheng Wang   +6 more
doaj   +1 more source

Orbital velocity [PDF]

arXiv, 2016
The trajectory and the orbital velocity are determined for an object moving in a gravitational system, in terms of fundamental and independent variables. In particular, considering a path on equipotential line, the elliptical orbit is naturally traced, verifying evidently the keplerian laws. The case of the planets of the solar system is presented.
arxiv