Results 61 to 70 of about 255,622 (355)

Efficacy of low-energy selective laser trabeculoplasty on the treatment of primary open angle glaucoma [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To investigate the efficacy of low-energy selective laser trabeculoplasty (SLT) on the treatment of primary open angle glaucoma (POAG) patients. METHODS: Outpatients with POAG who underwent 360-degree SLT using an initial energy of 0.3 mJ (total ...
Li Xu   +9 more
doaj   +1 more source

Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives [PDF]

open access: yes, 2019
The pathological aggregation and accumulation of tau, a microtubule-associated protein, is a common feature amongst more than 18 different neurodegenerative diseases that are collectively known as tauopathies.
Bucchieri, Fabio   +6 more
core   +1 more source

Stability analysis of a novel Delay Differential Equation of HIV Infection of CD4$^+$ T-cells [PDF]

open access: yesarXiv, 2021
In this paper, we investigate a novel 3-compartment model of HIV infection of CD4$^+$ T-cells with a mass action term by including two versions: one baseline ODE model and one delay-differential equation (DDE) model with a constant discrete time delay. Similar to various endemic models, the dynamics within the ODE model is fully determined by the basic
arxiv  

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden   +15 more
wiley   +1 more source

Age-Related Reference Intervals of the Main Biochemical and Hematological Parameters in C57BL/6J, 129SV/EV and C3H/HeJ Mouse Strains [PDF]

open access: yes, 2008
BACKGROUND: Although the mouse is the animal model most widely used to study the pathogenesis and treatment of human diseases, reference values for biochemical parameters are scanty or lacking for the most frequently used strains.
CITO G.   +6 more
core  

The neurocognitive gains of diagnostic reasoning training using simulated interactive veterinary cases [PDF]

open access: yes, 2019
The present longitudinal study ascertained training-associated transformations in the neural underpinnings of diagnostic reasoning, using a simulation game named “Equine Virtual Farm” (EVF).
Nassar, Maaly
core   +1 more source

Benefits of Zebrafish Xenograft Models in Cancer Research

open access: yesFrontiers in Cell and Developmental Biology, 2021
As a promising in vivo tool for cancer research, zebrafish have been widely applied in various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for cancer research that can be established quickly and requires only a small ...
Xingyu Chen   +7 more
doaj   +1 more source

Cases of orbital disease [PDF]

open access: yesThe Dublin Journal of Medical Science, 1873
n ...
openaire   +2 more sources

Stable Radical Polymers as New Electroactive Materials: Synthesis, Properties, and Emerging Applications

open access: yesAdvanced Functional Materials, EarlyView.
This review covers the recent advances in the synthesis and properties of stable radical polymers (SRPs) and presents their applications in electronics, magnetics, optoelectronics, and biomedicines. The review concludes with a discussion of the challenges in radical chemistry and functionalization, while shedding light on the groundbreaking potential ...
Yufeng Xiong   +11 more
wiley   +1 more source

EPR Methods for Biological Cu(II): L-Band CW and NARS [PDF]

open access: yes, 2015
: Copper has many roles in biology that involve the change of coordination sphere and/or oxidation state of the copper ion. Consequently, the study of copper in heterogeneous environments is an important area in biophysics. EPR is a primary technique for
Bennett, Brian, Kowalski, Jason M.
core   +2 more sources

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