Results 191 to 200 of about 12,783 (215)
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Orexins: a role in medullary sympathetic outflow
Regulatory Peptides, 2000Orexin A and B, also known as hypocretin 1 and 2, are two recently isolated hypothalamic peptides. As orexin-containing neurons are strategically located in the lateral hypothalamus, which has long been suspected to play an important role in feeding behaviors, initial studies were focused on the involvement of orexins in positive food intake and energy
Dun, Nae J. +5 more
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Orexin A but Not Orexin B Rapidly Enters Brain from Blood by Simple Diffusion
The Journal of Pharmacology and Experimental Therapeutics, 1999We determined the ability of orexin A and orexin B, recently discovered endogenous appetite enhancers, to cross the blood-brain barrier (BBB) of mice. Multiple time-regression analysis showed that an i.v. bolus of 125I-orexin A rapidly entered the brain from the blood, with an influx rate (Ki = 2.5 +/- 0.3 x 10(-4) ml/g.min) many times faster than that
A J, Kastin, V, Akerstrom
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Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1
New England Journal of Medicine, 2023Rafael del Río-Villegas
exaly
Effects of Orexin-A and Orexin-B on Renal Sodium Handling
International Journal of Pharmacology, 2006G. Wojcicka . +3 more
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Orexin neurons inhibit sleep to promote arousal
Nature Communications, 2022Roberto De Luca, Anne Venner, Dong Kong
exaly