Results 121 to 130 of about 361,283 (293)
Statistics for open reading frame (ORF) predictions.
, 2015 Statistics for open reading frame (ORF) predictions.
Yongang Yu (727925) +8 more
core +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li +3 more
wiley +1 more source
Expression and in vitro characterization of herpes simplex virus 1 (HSV-1) ORF P protein [PDF]
, 2006 Herpes simplex virus 1 (HSV-1) unspliced 8.3 latency associated transcript (LAT), which located in the long repeat sequences, has been shown to contain at least 16 open reading frames (ORF: A-P). One of these ORF, ORF P, maps almost entirely antisense to
Karimi, Ali., Nafisi, Mohammad Reza.
core +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Modified Vaccinia virus Ankara (MVA) is a potent vector for the development of vaccines and novel cancer treatment strategies. Since it is a non‐replicating virus in human recipients, high infective titers are required for therapeutic efficacy.
Linus G. Weber +5 more
wiley +1 more source
A Modular Micro‐Chemostat System for High‐Throughput Continuous Cultivations
Biotechnology and Bioengineering, EarlyView.This study presents and demonstrates a modular 12‐channel micro‐chemostat, designed to be used by Genesis, a Robot Scientist developed to automate scientific research in yeast systems biology. The bioreactor performance fulfilled the predefined requirements, and the empirical results from the biological experiments were consistent with the literature ...
Erik Y. Bjurström +7 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson +7 more
wiley +1 more source
Genomic sequence of mandarin fish rhabdovirus with an unusual small non-transcriptional ORF
, 2008 The complete genome of mandarin fish Siniperca chuatsi rhabdovirus (SCRV) was cloned and sequenced. It comprises 11,545 nucleotides and contains five genes encoding the nucleoprotein N, the phosphoprotein P, the matrix protein M, the glycoprotein G, and ...
Gui, Han-Farig +4 more
core +1 more source
A Homoleptic Copper(I) Acetylene Complex
Chemistry – A European Journal, EarlyView.Ligand substitution of weakly coordinated N2 in [(N2)Cu{Al(ORF)4}] (RF = C(CF3)3) leads to the homoleptic acetylene complex [Cu(C2H2)3]+[Al(ORF)4]−, which was characterized by single crystal x‐ray diffraction, NMR, and Raman spectroscopy, as well as by extensive quantum chemical calculations. ABSTRACT We report the synthesis and characterization of the
Julie Willrett +3 more
wiley +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract The diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) relies on detecting cells deficient in GPI‐anchored proteins and is currently based on manual, time‐consuming interpretation requiring specialized expertise. This study aimed to develop machine learning models to identify PNH clones in granulocytes and monocytes using flow cytometry ...
Felipe Magalhães Furtado +5 more
wiley +1 more source