Results 101 to 110 of about 467,774 (286)

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

open access: yesAdvanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang   +17 more
wiley   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

open access: yesAdvanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu   +7 more
wiley   +1 more source

Aging and Electrical Stability of DNTT Honey‐Gated OFETs

open access: yesAdvanced Electronic Materials, EarlyView.
DNTT honey‐gated organic transistors were fabricated and evaluated to assess short‐ and long‐term stability under electrical stress and aging. Short‐term transfer measurements (five days, 40 sweeps/day) showed minimal parameter shift, while extended measurements revealed gradual degradation over weeks.
Douglas H. Vieira   +8 more
wiley   +1 more source

Orf with photoaggravated eruption

open access: yesJAAD Case Reports, 2021
Christoffer Aam Ingvaldsen, MD, PhD   +2 more
doaj   +1 more source

Highly Stabilized Ni‐Rich Cathodes Enabled by Artificially Reversing Naturally‐Formed Interface

open access: yesAdvanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
The application of Ni‐rich cathode materials is obstructed by interfacial and structural instability. This work proposes a facile and cost‐effective Al‐based vapor‐phase surface reaction strategy on Ni‐rich cathode to maintain its structural integrity from near‐surface to bulk.
Jinjin Ma   +11 more
wiley   +1 more source

Evaluating oral reading fluency in English as a Second Language: A quantitative analysis

open access: yesReading & Writing
Background: There is a dearth of research on second language oral reading fluency (ORF) globally, particularly in Pakistan, both in theory and practice. No ORF scores are reported in any schools in Pakistan.
Maria F. Dogar   +3 more
doaj   +1 more source

CARE1, a TY3-gypsy long terminal repeat retrotransposon in the food legume chickpea (Cicer arietinum L) [PDF]

open access: yes, 2007
We report a novel Ty3-gypsy long terminal repeat retrotransposon CARE1 (_Cicer arietinum_ retro-element 1) in chickpea. This 5920-bp AT-rich (63%) element carries 723-bp 5' and 897-bp 3' LTRs respectively flanking an internal region of 4300-bp.
Kailash C. Upadhyaya, Manoj D. R. Rajput
core   +1 more source

Machine Learning Driven Inverse Design of Broadband Acoustic Superscattering

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multilayer acoustic superscatterers are designed using machine learning to achieve broadband superscattering and strong sound insulation. By incorporating a weighted mean absolute error into the loss function, the forward and inverse neural networks accurately map structural parameters to spectral responses.
Lijuan Fan, Xiangliang Zhang, Ying Wu
wiley   +1 more source

Phage ORF family recombinases: conservation of activities and involvement of the central channel in DNA binding.

open access: yesPLoS ONE, 2014
Genetic and biochemical evidence suggests that λ Orf is a recombination mediator, promoting nucleation of either bacterial RecA or phage Redβ recombinases onto single-stranded DNA (ssDNA) bound by SSB protein.
Fiona A Curtis   +11 more
doaj   +1 more source

Replication characteristics of herpes simplex virus type-1 (HSV-1) recombinants in 3 types of tissue cultures [PDF]

open access: yes, 2005
A complication in the analysis of the role of ICP34.5 gene in the herpes simplex virus type-1 (HSV-1) lifecycle is the presence of overlapping antisense gene, open reading frame P (ORF P), which is also deleted in HSV-1 ICP34.5 negative mutants.
Karimi, Ali., MacLean, Alasdair.
core  

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