Results 81 to 90 of about 361,283 (293)

ORF schießt Futurezone ab!

, 2010
http://blog.kooptech.de/2010/06/orf-schiesst-futurezone-ab [N]un ist die Futurezone zum Bauernopfer des neuen ORF-Gesetzes geworden, das praktisch zwischen ORF und dem Verband Österreichischer Zeitungen (VÖZ) ausgehandelt wurde. Der Deal: Für die Aufgabe
Klaus Graf
core  

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

Advanced Science, EarlyView.
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai, Jingyi Tang, Huan Rong, Yu Wang, Xiangyi Zhou, Can Xu, Jianhua Wang, Lili Li, Yue Wu, Fei Deng, Dan Yang, Xiao Yang, Renyan Li, Yongzhong Wu, Dongxi Xiang, Tingxiu Xiang   +15 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +2 more sources

Security Challenges and Nation Branding in Qatar: Capacities and Policies [PDF]

Faṣlnāmah-i Pizhūhish/hā-yi Rāhburdī-i Siyāsat
IntroductionOver the past three decades, significant transformations in the global landscape have profoundly influenced power dynamics, national security paradigms, and international political structures.
Ali akbar Asadi, Mohammd Orf
doaj   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

The Impact of Simulated Spectral Noise on Random Forest and Oblique Random Forest Classification Performance

Journal of Spectroscopy, 2018
Hyperspectral datasets contain spectral noise, the presence of which adversely affects the classifier performance to generalize accurately. Despite machine learning algorithms being regarded as robust classifiers that generalize well under unfavourable ...
Na’eem Hoosen Agjee, Onisimo Mutanga, Kabir Peerbhay, Riyad Ismail   +3 more
doaj   +1 more source

Non‐Coding Transcripts From Diversified Members of IgLec Family Protect Antiviral Effectors From Viral miRNA

Advanced Science, EarlyView.
The IgLec gene family generates both protein‐coding antiviral effectors and non‐coding transcripts. Upon viral infection, non‐coding transcripts are preferentially targeted by viral miR‐N48, thereby buffering protein‐coding isoforms from repression. Depletion of these decoy transcripts compromises antiviral defense, revealing a non‐coding RNA‐mediated ...
Ying Huang, Rui Shen, Xin Huang, Gu‐Qin Ji, Jiang‐Feng Lan, Qian Ren   +5 more
wiley   +1 more source

Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report

Virology Journal, 2009
An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis.
Jean Young-Hwa, Kim Hye-Ryoung, Lee Kyoung-Ki, Lee Kyung-Hyun, Roh In-Soon, Oem Jae-Ku, Lee O-Soo   +6 more
doaj   +1 more source

Die ewige ORF-Kritik

, 2019
„Die ewige ORF-Kritik: Wie die Politik journalistische Qualität beeinflusst“ Im Zentrum des Interesses dieser Arbeit steht die Kritik am öffentlich-rechtlichen Rundfunk in Österreich und wie die Politik die journalistische Qualität des ORF beeinflusst ...
Nahler, Alina
core  

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source