Results 91 to 100 of about 167,006 (281)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Activation of CXCL-8 Transcription by Hepatitis E Virus ORF-1 via AP-1

Mediators of Inflammation, 2015
Hepatitis E virus (HEV) is a small nonenveloped single-stranded positive-sense RNA virus and is one of the major causes for acute hepatitis worldwide. CXCL-8 is a small multifunctional proinflammatory chemokine.
Zhubing Li, Lu Chen, Qiang Liu
doaj   +1 more source

In vitro inhibition of transmissible gastroenteritis coronavirus replication in swine testicular cells by short hairpin RNAs targeting the ORF 7 gene

Virology Journal, 2012
Background Transmissible gastroenteritis (TGE) is a highly contagious viral disease of swine, characterized by severe vomiting, diarrhea, and high mortality.
He Lei, Zhang Yan-ming, Dong Ling-juan, Cheng Min, Wang Jing, Tang Qing-hai, Wang Gang   +6 more
doaj   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

In vitro interaction and colocalization of HSV-1 ORF P with a cellular splicing factor (SC35) using pulldown assay [PDF]

, 2005
Herpes simplex virus type-1 (HSV-1) causes a variety of diseases in human. This virus is a neurotropic pathogen of human that establishes latent infection in the sensory ganglia innervating the site of primary infection. A number of genes including ICP34.
Karimi, Ali., Salehi, Rasoul.
core  

Green Synthesis of ZnO Nanoparticles From Spirulina platensis: Antimicrobial and Cytotoxic Evaluation With Molecular Docking Studies

ChemistryOpen, EarlyView.
Algal‐extract‐derived ZnO nanoparticles show shape anisotropy and are bio capped by phytochemicals. These green‐synthesized NPs strongly inhibit S. aureus and K. pneumoniae biofilms. Molecular docking suggests stable binding of surface biomolecules to microbial targets, highlighting synergistic antibacterial mechanisms.
Muhammad Rizwan, Izaz Khan, Syed Sikandar Shah, Amir hamza khan, Abdurahman Hajinur Hirad, Saira Naz, Arshad Farid, Taimoor Khan, Said Hassan   +8 more
wiley   +1 more source

Heterologous expression of HCoV-HKU1 ORF 7b by mouse hepatitis virus protects against severe disease during murine infection.

PLoS Pathogens
Coronaviruses express a repertoire of accessory proteins for evading host immune responses. A small internal (I) accessory gene overlaps with the nucleocapsid (N) gene in an alternative reading frame of viruses that belong to the genus Betacoronavirus ...
Chaminda D Gunawardene, Isha Pandey, Shruti Chatterjee, Yoatzin Peñaflor-Téllez, Abby Odle, Abbey N Warren, Adriana Messyasz, Ricardo Rajsbaum, Alan Sariol, Lok-Yin Roy Wong   +9 more
doaj   +1 more source

Answer: Orf virus infection [PDF]

Annals of Saudi Medicine, 2020
Monica Garcia-Arpa, Lucia Gonzalez-Ruiz, Luis Gomez-Sanchez, Marcos Carmona-Rodriguez   +3 more
openaire   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

Pest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden, Gözde Güney, Michael Rostás, Stefan Scholten   +3 more
wiley   +1 more source

Exploring First Interactions Between Ostreid Herpesvirus 1 (OsHV-1) and Its Host, Crassostrea gigas: Effects of Specific Antiviral Antibodies and Dextran Sulfate

Frontiers in Microbiology, 2019
Viral entry mechanisms of herpesviruses constitute a highly complex process which implicates several viral glycoproteins and different receptors on the host cell surfaces. This initial infection stage was currently undescribed for Ostreid herpes virus 1 (
Claire Martenot, Nicole Faury, Benjamin Morga, Lionel Degremont, Jean-Baptiste Lamy, Maryline Houssin, Tristan Renault   +6 more
doaj   +1 more source