Results 161 to 170 of about 167,006 (281)

The whole genome analysis of four Orf virus strains from Europe and South America. [PDF]

open access: yesVirus Evol
Cacciabue M   +8 more
europepmc   +1 more source

RNA‐Based Therapies for Inherited Metabolic Disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri   +5 more
wiley   +1 more source

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

open access: yesJEADV Clinical Practice, Volume 5, Issue 1, Page 250-253, March 2026.
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González   +6 more
wiley   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng   +8 more
wiley   +1 more source

Rapid Onsite Visual Detection of Orf Virus Using a Recombinase-Aided Amplification Assay. [PDF]

open access: yesLife (Basel), 2023
Cui H   +8 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Establishment of a sheep immortalization cell line for generating and amplifying Orf virus recombinants. [PDF]

open access: yesFront Vet Sci, 2022
Sun S   +11 more
europepmc   +1 more source

Are Tetrapleura tetraptera Phytochemicals Druggable Against SARS‐CoV‐2 Papain‐Like Protein? A Computational Approach

open access: yesNew Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
SARS‐CoV2 Omicron and its substrains are still a critical global health issue and extremely contagious, even with widespread vaccination efforts. Hospitalizations and mortality rates linked to these variants are still prevalent. Current therapeutic options face challenges, including low effectiveness, suboptimal pharmacokinetics, and drug resistance ...
Frank Eric Tatsing Foka   +1 more
wiley   +1 more source

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