Results 201 to 210 of about 122,503 (234)
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Virus particles and antigens in experimental Orf scabs
Archiv f�r die gesamte Virusforschung, 1973Sequential observations of experimentally induced orf scabs on lambs revealed that complement-fixing antigens, precipitating antigens and virus particles all reached peak levels within one to two weeks. The most sensitive diagnostic technique was the detection of complement-fixing antigen.
C H, Romero-Mercado +4 more
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Gene homology between orf virus and smallpox variola virus
Virus Genes, 1996About 47% identity was observed between the deduced amino acid sequences of a protein encoded by a gene of the parapoxvirus orf virus (OV) strain NZ2 and a 6 kDa protein of unknown function reported to be produced by an open reading frame expressed early after infection by the orthopoxvirus Western Reserve vaccinia virus (VAC); the open reading frame ...
A A, Mercer, K M, Fraser, J J, Esposito
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A homologue of retroviral pseudoproteases in the parapoxvirus, orf virus
Virology, 1989The nucleotide sequence of a near-terminal region of orf virus DNA was determined. Examination of the sequence revealed an open reading frame encoding a peptide with significant amino acid homology to the pseudoprotease domains recently identified in a number of retroviruses including mouse mammary tumor virus, simian Mason-Pfizer virus, maedi-visna ...
A A, Mercer +3 more
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Erythema multiforme after orf virus infection
Pediatric Dermatology, 2018AbstractThe case of a 6‐year‐old boy with multiple, target‐shaped lesions and a crusted nodule on his right index finger is presented. Based on clinical findings and the patient's recent contact with sheep and goats, a diagnosis of orf disease associated with erythema multiforme was suspected.
Angella López‐Cedeño +5 more
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Immune responses of patients to orf virus infection
British Journal of Dermatology, 1994Orf is a disease of sheep and goats which is caused by a parapox virus. It can be transmitted to humans, and is considered an occupational hazard by those handling sheep. In this paper we present the first report of both cell-mediated and humoral immune responses to naturally acquired orf virus infection in humans.
D L, Yirrell, J P, Vestey, M, Norval
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Cytotoxic Antibodies in Orf Virus Infection of Sheep
Zentralblatt für Veterinärmedizin Reihe B, 2010Summary Serum samples from sheep experimentally or naturally infected with orf virus were tested for cytotoxic antibody by a 51Cr release test. Cytotoxic antibodies developed within one month of experimental infection, persisted for 2—4 weeks and did not rise significantly in titre after a first or second re-exposure to virus 9 or 16 weeks later ...
G, Koptopoulos, H W, Reid, I, Pow
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Molecular characterization of Brazilian isolates of orf virus
Veterinary Microbiology, 2000Outbreaks of an epidermic disease suggesting parapox virus infections have been observed in all major herds of sheep and goats from different geographical areas of Brazil. Clinical samples (dried scabs) were collected and orf virus was isolated and characterized by electron microscopy in previous work.
C, Mazur +3 more
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Orf virus infection in pregnancy.
South Dakota journal of medicine, 1994Orf virus infection is endemic among sheep and goats, and can occur in humans who handle these animals. Orf virus infection in humans causes a characteristic skin lesion, and systemic symptoms can occur. Very little is known about Orf virus infection in human pregnancy.
W J, Watson, M W, Meyer, D L, Madison
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Orf virus: A promising new therapeutic agent
Reviews in Medical Virology, 2018SummaryThe orf virus (ORFV) is a zoonotic, epitheliotropic, DNA parapoxvirus that infects principally sheep and goats. Exposure of animals to the virus or immunization by an ORFV preparation can accentuate the severity of disease, which has provoked an interest in the underlying cellular, virological, and molecular mechanisms.
Ruixue Wang +3 more
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Generation and Selection of Orf Virus (ORFV) Recombinants
2016Orf virus (ORFV) is an epitheliotropic poxvirus, which belongs to the genus Parapoxvirus. Among them the highly attenuated, apathogenic strain D1701-V is regarded as a promising candidate for novel virus vector vaccines. Our recent work demonstrated that those ORFV-based recombinants were able to induce protective, long-lasting immunity in various ...
Hanns-Joachim, Rziha +2 more
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