Organ-on-a-Chip and Lab-on-a-Chip Technologies in Cardiac Tissue Engineering [PDF]
BiomimeticsMicrofluidic technologies have ushered in a new era in cardiac tissue engineering, providing more predictive in vitro models compared to two-dimensional culture studies. This review examines Organ-on-a-Chip (OoC) and Lab-on-a-Chip (LoC) platforms, with a
Daniele Marazzi +3 more
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Organ-on-a-Chip: A Roadmap for Translational Research in Human and Veterinary Medicine. [PDF]
Int J Mol SciIn this review we offer a guide to organ-on-chip (OoC) technologies, covering the full experimental pipeline, from organoid derivation and culture, through microfluidic device fabrication and design strategies, to perfusion systems and data acquisition ...
Surina S +5 more
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Advances and Applications of Organ-on-a-Chip and Tissue-on-a-Chip Technology. [PDF]
Bioengineering (Basel)Organ-on-a-chip (OoC) or tissue-on-a-chip (ToC) technologies represent a significant advancement in enabling modeling of human organ and tissue physiology for medical study, although further development is required for these technologies to reach ...
Moore M, Sriram S, Ku J, Li Y.
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Recent Progress in PDMS-Based Microfluidics Toward Integrated Organ-on-a-Chip Biosensors and Personalized Medicine. [PDF]
Biosensors (Basel)The organ-on-a-chip (OoC) technology holds significant promise for biosensors and personalized medicine by enabling the creation of miniature, patient-specific models of human organs.
Alghannam F +6 more
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Organ-on-a-chip and the kidney
Kidney Research and Clinical Practice, 2015 Traditional approaches to pathophysiology are advancing but still have many limitations that arise from real biologic systems and their associated physiological phenomena being too complicated.
Sejoong Kim, Shuichi Takayama
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Organ-on-a-chip: future of female reproductive pathophysiological models [PDF]
Journal of NanobiotechnologyThe female reproductive system comprises the internal and external genitalia, which communicate through intricate endocrine pathways. Besides secreting hormones that maintain the female secondary sexual characteristics, it also produces follicles and ...
Zhi-Min Deng +6 more
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Reproductive organ on-a-chip technologies and assessments of the fetal-maternal interface. [PDF]
Front Lab Chip TechnolIn this review, we discuss recent reproductive organ-on-a-chip (OoC) experiments that encompass multiple target areas of investigation, including model fabrication strategies, transport mechanisms, and immunology.
Richards HA +3 more
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Organ-on-a-Chip Applications in Microfluidic Platforms. [PDF]
Micromachines (Basel)Microfluidic technology plays a crucial role in organ-on-a-chip (OoC) systems by replicating human physiological processes and disease states, significantly advancing biomedical research and drug discovery. This article reviews the design and fabrication processes of microfluidic devices.
An L, Liu Y, Liu Y.
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Comparison of cytokine responses to group B <i>Streptococcus</i> infection in a human maternal-fetal interface organ-on-a-chip system and <i>ex vivo</i> culture model of human gestational membranes. [PDF]
Infect ImmunAdverse pregnancy outcomes represent a global health burden. Bacterial infection and subsequent inflammation in gestational membranes lead to immunological and physiological changes that contribute to adverse pregnancy outcomes. Although animal models of
Kirk LA +10 more
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Micromachines, 2021 The understanding that systemic context and tissue crosstalk are essential keys for bridging the gap between in vitro models and in vivo conditions led to a growing effort in the last decade to develop advanced multi-organ-on-a-chip devices.
Yoel Goldstein +7 more
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