Results 91 to 100 of about 61,131 (327)

Organ on a Chip (Kidney)

International Journal of Innovative Technology and Exploring Engineering, 2019
Organ on a chip (OOC) is called an artificial organ, and it is a multi-channel the purpose of the chip is to absence in vivo the chip consists of both digital and analog part digital part mainly dedicated to the communication protocol, it also includes power management with clock switches; silicon is a promising material due to its reliable and ...
M Raj Kumar*, Roji Marjorie
openaire   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Approaches to in vitro tissue regeneration with application for human disease modeling and drug development [PDF]

, 2014
Reliable in vitro human disease models that capture the complexity of in vivo tissue behaviors are crucial to gain mechanistic insights into human disease and enable the development of treatments that are effective across broad patient populations.
Borenstein, Jeffrey T., Ebrahimkhani, Mohammad Reza, Griffith, Linda G., Lauffenburger, Douglas A., Young, Carissa L.   +4 more
core   +1 more source

Developments and Applications of Liver-on-a-Chip Technology—Current Status and Future Prospects

Biomedicines
Background/Objectives: Liver-on-a-chip (LiOC) technology is increasingly recognized as a transformative platform for modeling liver biology, disease mechanisms, drug metabolism, and toxicity screening.
Joseph Mugaanyi, Jing Huang, Jiongze Fang, Arthur Musinguzi, Caide Lu, Zaozao Chen   +5 more
doaj   +1 more source

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

Sensors, 2015
Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate ...
Ana Rubina Perestrelo, Ana C. P. Águas, Alberto Rainer, Giancarlo Forte   +3 more
doaj   +1 more source

Impact of Neurons on Patient-Derived Cardiomyocytes Using Organ-On-A-Chip and iPSC Biotechnologies

bioRxiv, 2022
In the heart, cardiac function is regulated by the autonomic nervous system (ANS) that extends through the myocardium and establish junctions at the sinus node and ventricular levels.
Albin A Bernardin, Sarah Colombani, Antoine Rousselot, Virginie Andry, Y. Goumon, H. Delanoë-Ayari, C. Pasqualin, B. Brugg, E. Jacotot, J. Pasquié, A. Lacampagne, A. Meli   +11 more
semanticscholar   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Development of flow focusing device for the visualization of leukocyte rolling adhesion [PDF]

, 2018
La microfluídica es un área de la microtecnología basada en chips de PDMS que está siendo utilizada cada vez más en multitud de aplicaciones. Una de estas aplicaciones es la investigación biomédica.
Morales Navarrete, Pablo
core  

Organoid-on-a-chip (OrgOC): Advancing cystic fibrosis research

Materials Today Bio
Cystic fibrosis (CF) is an autosomal recessive disorder resulting from impaired anion transport in the epithelium of multiple organs, thereby affecting various physiological functions throughout the body.
Minjie Zheng, Elisa Erice, Huiyi Wang, Lei Zhang, Charles H. Lawrie   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source