Results 51 to 60 of about 56,595 (259)

Organoid-on-a-chip (OrgOC): Advancing cystic fibrosis research

open access: yesMaterials Today Bio
Cystic fibrosis (CF) is an autosomal recessive disorder resulting from impaired anion transport in the epithelium of multiple organs, thereby affecting various physiological functions throughout the body.
Minjie Zheng   +4 more
doaj   +1 more source

Oxide‐Free Titanium Coatings by Wire Arc Spraying in a Silane‐Doped Inert Atmosphere

open access: yesAdvanced Engineering Materials, EarlyView.
A silane‐doped argon atmosphere enables the production of oxide‐free titanium coatings via twin‐wire arc spraying at ambient pressure. This innovative approach eliminates residual oxygen, creating process conditions that prevent oxidation and nitride formation.
Manuel Rodriguez Diaz   +4 more
wiley   +1 more source

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

open access: yesSensors, 2015
Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate ...
Ana Rubina Perestrelo   +3 more
doaj   +1 more source

Organ-on-a-chip for assessing environmental toxicants [PDF]

open access: yesCurrent Opinion in Biotechnology, 2017
Man-made xenobiotics, whose potential toxicological effects are not fully understood, are oversaturating the already-contaminated environment. Due to the rate of toxicant accumulation, unmanaged disposal, and unknown adverse effects to the environment and the human population, there is a crucial need to screen for environmental toxicants. Animal models
Soohee, Cho, Jeong-Yeol, Yoon
openaire   +2 more sources

Engineered Mycelial Scaffolds With Tunable Ultraviolet Protection, Wettability, Thermal Stability, and Spatial Mechanics

open access: yesAdvanced Engineering Materials, EarlyView.
Fungal mycelia grown into biodegradable scaffolds and infused with titania nanoparticles show enhanced ultraviolet shielding, thermal protection, and surface nonwettability. Properties were tuned by drying methods, revealing structure–function relationships.
Juwon S. Afolayan   +2 more
wiley   +1 more source

Engineering cell heterogeneity into organs-on-a-chip [PDF]

open access: yesLab on a Chip, 2018
To improve predictive efficacy of organ-on-a-chip devices, developers must consider cell heterogeneity.
David R. Mertz   +2 more
openaire   +2 more sources

Analyzing Electronic Excitations and Exciton Binding Energies in Y6 Films

open access: yesAdvanced Functional Materials, EarlyView.
The Y6 molecule is used for increasing the efficiency of organic solar cells. The exciton binding energy is calculated for ensembles of Y6 molecules that are representative of the typically used films. The calculations show that the excitons typically spread out over many molecules.
Sahar Javaid Akram   +2 more
wiley   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Biomimetic gender-specific human skin model based on gonads/epidermis-on-a-chip

open access: yesBioactive Materials
The development of bionic skin is crucial for progressing our understanding of skin physiology and pathologies, while the precise replication of human skin features in skin models remains a challenge.
Xiangyi Wu   +4 more
doaj   +1 more source

Synergistic Engineering: Organoids Meet Organs-on-a-Chip [PDF]

open access: yesCell Stem Cell, 2017
Organoid technology and organ-on-a-chip engineering have emerged as two distinct approaches for stem cell-derived 3D tissue preparation. Their strategic integration can address each approach's limitations and provide a path toward a superior, synergistic strategy of constructing tissues that will truly deliver on the promise of regenerative and ...
Takanori, Takebe   +2 more
openaire   +2 more sources

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