Results 41 to 50 of about 1,028,257 (352)
Journal of Functional Biomaterials, 2018 (1) Background: Intervertebral disc (IVD) repair represents a major challenge. Using functionalised biomaterials such as silk combined with enforced hydrogels might be a promising approach for disc repair.
Daniela A. Frauchiger +7 more
doaj +1 more source
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents [PDF]
, 2015 Systemic absorption and metabolism of drugs in the small intestine, metabolism by the liver as well as excretion by the kidney are key determinants of efficacy and safety for therapeutic candidates. However, these systemic responses of applied substances
Bauer, Sophie +13 more
core +1 more source
Developing a Tooth in situ Organ Culture Model for Dental and Periodontal Regeneration Research
Frontiers in Bioengineering and Biotechnology, 2021 In this study we have realized the need for an organ culture tooth in situ model to simulate the tooth structure especially the tooth attachment apparatus.
Reem El-Gendy +11 more
doaj +1 more source
Dynamic loading, matrix maintenance and cell injection therapy of human intervertebral discs cultured in a bioreactor [PDF]
European Cells & Materials, 2016 Low back pain originating from intervertebral disc (IVD) degeneration affects the quality of life for millions of people, and it is a major contributor to global healthcare costs. Long-term culture of intact IVDs is necessary to develop ex vivo models of
DH Rosenzweig +8 more
doaj +1 more source
CULTURES OF ORGANIZED TISSUES [PDF]
Journal of Experimental Medicine, 1922 An artificial organism, if one may so term it, composed of a complex of tissues, was cultivated for a long period of time. Small fragments of intestine from chick embryos 20 to 21 days old were placed in a suitable medium. The epithelium proliferated and completely covered the fragment of intestine after 4 to 6 days. A small body was thus formed, round
openaire +2 more sources
Frontiers in Bioengineering and Biotechnology, 2020 Discogenic low back pain (LBP) is a main cause of disability and inflammation is presumed to be a major driver of symptomatic intervertebral disc degeneration (IDD).
Zhen Li +13 more
doaj +1 more source
Journal of Investigative Surgery, 2022 Aim: This review summarized the recent intervertebral disc degeneration (IDD) models and described their advantages and potential disadvantages, aiming to provide an overview for the current condition of IDD model establishment and new ideas for new ...
Yidian Wang +7 more
doaj +1 more source
Sorry Buddy, But Your Name Isn\u27t on the List: Fear and the Ethics of Organ Donation in Film [PDF]
, 2012 The fear of death and illness is a powerful motivator. When taking into account the ethical reasoning that drives organ transplantation and procurement practices, it is persuasive enough to sway minds and corrupt pure reason.
Callis, Ted
core +1 more source
Provider-initiated symptom screening for tuberculosis in Zimbabwe: diagnostic value and the effect of HIV status. [PDF]
, 2010 OBJECTIVE: To assess the diagnostic value of provider-initiated symptom screening for tuberculosis (TB) and how HIV status affects it. METHODS: We performed a secondary analysis of randomly selected participants in a community-based TB-HIV prevalence ...
Bandason, Tsitsi +11 more
core +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source