Results 31 to 40 of about 4,938,266 (305)

Improvements in in vitro spermatogenesis: oxygen concentration, antioxidants, tissue-form design, and space control

The Journal of Reproduction and Development, 2023
Incorporation of bovine serum-derived albumin formulation (AlbuMAX) into a basic culture medium, MEMα, enables the completion of in vitro spermatogenesis through testicular tissue culture in mice.
Takehiko OGAWA, Takafumi MATSUMURA, Tatsuma YAO, Hiroshi KIMURA, Kiyoshi HASHIMOTO, Yu ISHIKAWA-YAMAUCHI, Takuya SATO   +6 more
doaj   +1 more source

Usefulness of the organ culture system in the in vitro diagnosis of coeliac disease: A multicentre study

, 2006
Objective. Diagnosis of coeliac disease is based on the presence of villous atrophy which recovers following a gluten-free diet. The presence of circulating antiendomysial antibodies as well as their disappearance after a gluten-free diet supports the ...
Maria Teresa Bardella, Maurizio Gasparin, Carmen Ribes Koninckx, L. Di Prima, Daniela Renzi, Donatella Barisani, Emilia Sugai, ANANIA, Maria Cristina, E. Multicentre Organ Culture System Study Group Bravi, Ester Donat Aliaga, Luigi Sabbatella, Antonio Carroccio, PICARELLI, Antonio, DI TOLA, MARCO, Antonio Calabro, Julio Cesar Bai   +15 more
core   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Genipin-Enhanced Fibrin Hydrogel and Novel Silk for Intervertebral Disc Repair in a Loaded Bovine Organ Culture Model

Journal of Functional Biomaterials, 2018
(1) Background: Intervertebral disc (IVD) repair represents a major challenge. Using functionalised biomaterials such as silk combined with enforced hydrogels might be a promising approach for disc repair.
Daniela A. Frauchiger, Rahel D. May, Ezgi Bakirci, Adel Tekari, Samantha C. W. Chan, Michael Wöltje, Lorin M. Benneker, Benjamin Gantenbein   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Developing a Tooth in situ Organ Culture Model for Dental and Periodontal Regeneration Research

Frontiers in Bioengineering and Biotechnology, 2021
In this study we have realized the need for an organ culture tooth in situ model to simulate the tooth structure especially the tooth attachment apparatus.
Reem El-Gendy, Reem El-Gendy, Sarah Junaid, Stephen K. L. Lam, Karen M. Elson, Karen M. Elson, Joanne L. Tipper, Joanne L. Tipper, Richard M. Hall, Eileen Ingham, Eileen Ingham, Jennifer Kirkham   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Dynamic loading, matrix maintenance and cell injection therapy of human intervertebral discs cultured in a bioreactor [PDF]

European Cells & Materials, 2016
Low back pain originating from intervertebral disc (IVD) degeneration affects the quality of life for millions of people, and it is a major contributor to global healthcare costs. Long-term culture of intact IVDs is necessary to develop ex vivo models of
DH Rosenzweig, R Gawri, J Moir, L Beckman, D Eglin, T Steffen, PJ Roughley, JA Ouellet, L Haglund   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Glucose concentration modulates bovine intervertebral disc response under physiological loading

Frontiers in Bioengineering and Biotechnology
IntroductionEx vivo organ culture is a widely accepted model in intervertebral disc (IVD) research, providing valuable insights into pathology and potential new treatments.
D. Zuncheddu, D. Zuncheddu, M. Muerner, M. Muerner, K. Klavins, K. Klavins, M. J. Stoddart, L. B. Creemers, S. Grad, S. Grad   +9 more
doaj   +1 more source