Results 51 to 60 of about 5,802,173 (351)

Dynamic loading, matrix maintenance and cell injection therapy of human intervertebral discs cultured in a bioreactor [PDF]

open access: yesEuropean Cells & Materials, 2016
Low back pain originating from intervertebral disc (IVD) degeneration affects the quality of life for millions of people, and it is a major contributor to global healthcare costs. Long-term culture of intact IVDs is necessary to develop ex vivo models of
DH Rosenzweig   +8 more
doaj   +1 more source

Microsensor systems for cell metabolism - from 2D culture to organ-on-chip.

open access: yesLab on a Chip, 2018
Microsensor systems for cell metabolism are essential tools for investigation and standardization in cell culture. Electrochemical and optical read-out schemes dominate, which enable the marker-free, continuous, online recording of transient effects and ...
J. Kieninger   +3 more
semanticscholar   +1 more source

Breakthroughs and Applications of Organ-on-a-Chip Technology

open access: yesCells, 2022
Organ-on-a-chip (OOAC) is an emerging technology based on microfluid platforms and in vitro cell culture that has a promising future in the healthcare industry. The numerous advantages of OOAC over conventional systems make it highly popular. The chip is
Mufeeda C. Koyilot   +14 more
semanticscholar   +1 more source

Preclinical ex-vivo Testing of Anti-inflammatory Drugs in a Bovine Intervertebral Degenerative Disc Model

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Discogenic low back pain (LBP) is a main cause of disability and inflammation is presumed to be a major driver of symptomatic intervertebral disc degeneration (IDD).
Zhen Li   +13 more
doaj   +1 more source

Intervertebral Disc Degeneration Models for Pathophysiology and Regenerative Therapy -Benefits and Limitations

open access: yesJournal of Investigative Surgery, 2022
Aim: This review summarized the recent intervertebral disc degeneration (IDD) models and described their advantages and potential disadvantages, aiming to provide an overview for the current condition of IDD model establishment and new ideas for new ...
Yidian Wang   +7 more
doaj   +1 more source

Sorry Buddy, But Your Name Isn\u27t on the List: Fear and the Ethics of Organ Donation in Film [PDF]

open access: yes, 2012
The fear of death and illness is a powerful motivator. When taking into account the ethical reasoning that drives organ transplantation and procurement practices, it is persuasive enough to sway minds and corrupt pure reason.
Callis, Ted
core   +1 more source

Meeting report: a hard look at the state of enamel research. [PDF]

open access: yes, 2017
The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D   +13 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Plant Cellular and Molecular Biotechnology: Following Mariotti's Steps [PDF]

open access: yes, 2019
This review is dedicated to the memory of Prof. Domenico Mariotti, who significantly contributed to establishing the Italian research community in Agricultural Genetics and carried out the first experiments of Agrobacterium-mediated plant genetic ...
Caretto, Sofia   +11 more
core   +1 more source

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