ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun +10 more
wiley +1 more source
Immune Cell Responses to Fluid Shear: Overview and Design Considerations for <i>In Vitro</i> Modeling. [PDF]
Ginter EL, Hind LE.
europepmc +1 more source
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng +17 more
wiley +1 more source
Development of a fluorescent reporter strain to facilitate studies of <i>Borrelia burgdorferi</i> pathogenesis. [PDF]
Huckaby AB +19 more
europepmc +1 more source
The Mind From Within: Visceral Roots of Human Cognition
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti +1 more
wiley +1 more source
Leveraging Microphysiological Systems to Facilitate Neutrophil-Based Cancer Immunotherapy. [PDF]
Shao S, Diehl MI, Jones CN.
europepmc +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
Feasibility and clinical efficacy of minimally invasive techniques in the treatment of type Ⅱ/Ⅲ brucellar spondylitis. [PDF]
Yang X +5 more
europepmc +1 more source
Integrating mechanical cues in <i>in vitro</i> models of immune-related fibrotic diseases. [PDF]
Song C +8 more
europepmc +1 more source
Direct Effects of 308-nm Excimer Light on Keratinocyte Proliferation and Differentiation in Human Organ-Cultured Skin. [PDF]
Okazaki A +3 more
europepmc +1 more source

