Results 71 to 80 of about 1,435,862 (389)

Interferon-gamma FlowSpot assay for the measurement of the T-cell response to cytomegalovirus

Heliyon, 2023
Objectives: We describe a new method, FlowSpot, to assess CMV-specific T-cell response by quantification of interferon-gamma (IFN-γ). CMV-specific, T-cell-released IFN-γ was captured by flow beads and measured via flow cytometry. In the present study, we
Qianyu Ye, Jiali Wang, Meijing Chen, Weijian Nie, Huanxi Zhang, Xiaojun Su, Liuting Ling, Xiangjun Liu, Longshan Liu, Changxi Wang, Yifang Gao   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

THE “NEW BODY SNATCHERS”: ANALYZING THE EFFECT OF PRESUMED CONSENT ORGAN DONATION LAWS ON PRIVACY, AUTONOMY, AND LIBERTY [PDF]

, 2011
This Note examines, in three parts, presumed consent laws as they pertain to organ donation. Part I discusses presumed consent and explains the salient features of presumed consent laws.
Liddy, Maryellen
core   +1 more source

Does the Presence of a Measurable Blood Alcohol Level in a Potential Organ Donor Affect the Outcome of Liver Transplantation? [PDF]

, 1991
The widespread application of hepatic transplantation has created a tremendous demand for donor organs. An assessment of donor parameters is thought to be important in selecting good donors; however, the criteria utilized have not been standardized. This
Ascher NL, Blendis LM, Demetris AJ, Kakizoe S, Maddrey WC, Makowka L, Mimeault R, Mora NP, Schenker S, Starzl TE   +9 more
core   +1 more source

Evaluating the efficacy of basiliximab versus no induction in low-immunological-risk kidney transplant recipients: a propensity score matched analysis

Renal Failure
Background The optimal use of induction therapy in low-immunological-risk kidney transplant recipients (KTRs) remains uncertain. While Basiliximab (BSX) is widely utilized, its comparative outcomes with no induction therapy require further evaluation ...
Dahao Zhang, Jiqiu Wen, Jianhui Dong, Rong Ma, Shijian Li, Jihua Wu, Ning Wen, Zhiying Lei, Haibin Li, Jun Yin, Xuyong Sun   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Association Between Three Lung Donor Scores and Lung Acceptance in DBD and DCD Donors

Transplant International
The use of extended criteria donors (ECD) has become increasingly important in lung transplantation to address organ donor shortages. To better assess lung graft quality and optimize donor selection, several scores have been developed.
Fabian Iten, Julius Weiss, Simon Schwab, Franziska Beyeler, Thorsten Krueger, Angela Koutsokera, Macé Schuurmans, Isabelle Opitz, György Lang, Franz Immer   +9 more
doaj   +1 more source

New Blood Borne Virus Infections Among Organ Transplant Recipients: A Data-Linked Cohort Study Examining Transmissions and De Novo Infections

International Journal of Population Data Science, 2020
Introduction Solid organ transplant recipients are at risk of infections, which may be either derived through transplantation or acquired later. Blood-borne viruses (BBV) are a particular concern for donor-derived transmissions.
Karen MJ Waller, Nicole L De La Mata, James A Hedley, Brenda M Rosales, Michael J O’Leary, Elena Cavazzoni, Vidiya Ramachandran, William D Rawlinson, Patrick J Kelly, Kate R Wyburn, Angela C Webster   +10 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

"You have to die first": exploring the thoughts and feelings on organ donation of British women who have not signed up to be donors [PDF]

, 2016
Four White British women who had not signed up to be organ donors were interviewed in depth to investigate their feelings on organ donation. Transcripts were analysed using Interpretative Phenomenological Analysis to reveal how the ability to detach from
Britton, Heather P., Nizza, Isabella, Smith, Jonathan A.   +2 more
core   +1 more source