Results 71 to 80 of about 1,391,587 (398)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Liver steatosis in brain death donors

Вестник трансплантологии и искусственных органов, 2021
Aim. To study the frequency of fatty hepatosis in liver biopsies of consecutive brain death donors before cold preservation. Materials and methods.
D. V. Voronov, M. G. Minina, A. K. Chomaev, I. M. Iljinsky, O. M. Tsirulnikova   +4 more
doaj   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Soliciting organ donations by medical personnel and organ donation coordinators: A factor analysis.

PLoS ONE, 2021
The literature on organ donation in Taiwan lacks a discussion of the roles of medical staff, organ donors, and transplant coordinators in organ donation. The biggest plight of organ donation is lack of the organ donations.
Yao-Mei Chuang, Shan-Shan Yeh, Chi-Fen Tseng, Chie-Chien Tseng   +3 more
doaj   +1 more source

Attitudes towards organ donation in Malta in the last decade [PDF]

, 2006
Organ transplantation is possibly one of the few cases when even though the medical professionals have the expertise to carry out transplants of certain organs, and even though a person may have financial resources to cover every possible cost, the ...
Lauri, Mary Anne
core  

Ethics, organ donation and tax: a proposal [PDF]

, 2011
Five arguments are presented in favour of the proposal that people who opt in as organ donors should receive a tax break. These arguments appeal to welfare, autonomy, fairness, distributive justice and self-ownership, respectively.
Lippert-Rasmussen, Kasper, Petersen, Thomas Søbirk   +1 more
core   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Organ donation. [PDF]

BMJ, 1990
D W, Evans, D J, Hill
  +8 more sources

The First Case of Ischemia-Free Kidney Transplantation in Humans

Frontiers in Medicine, 2019
Background: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954.
Xiaoshun He, Xiaoshun He, Xiaoshun He, Guodong Chen, Guodong Chen, Guodong Chen, Zebin Zhu, Zebin Zhu, Zebin Zhu, Zhiheng Zhang, Zhiheng Zhang, Zhiheng Zhang, Xiaopeng Yuan, Xiaopeng Yuan, Xiaopeng Yuan, Ming Han, Ming Han, Ming Han, Qiang Zhao, Qiang Zhao, Qiang Zhao, Yitao Zheng, Yitao Zheng, Yitao Zheng, Yunhua Tang, Yunhua Tang, Yunhua Tang, Shanzhou Huang, Shanzhou Huang, Shanzhou Huang, Linhe Wang, Linhe Wang, Linhe Wang, Otto B. van Leeuwen, Xiaoping Wang, Xiaoping Wang, Xiaoping Wang, Chuanbao Chen, Chuanbao Chen, Chuanbao Chen, Liqiu Mo, Xingyuan Jiao, Xingyuan Jiao, Xingyuan Jiao, Xianchang Li, Xianchang Li, Xianchang Li, Xianchang Li, Changxi Wang, Changxi Wang, Changxi Wang, Jiefu Huang, Jiefu Huang, Jun Cui, Zhiyong Guo, Zhiyong Guo, Zhiyong Guo   +56 more
doaj   +1 more source

Serum Soluble B Cell-Activating Factor Is a Non-Invasive Biomarker of Antibody-Mediated Rejection in Kidney Allograft With Satisfactory Risk Stratification Performance But Negligible Diagnostic Value

Frontiers in Immunology, 2022
ObjectivesB cell-activating factor (BAFF), which is critical in the activation and differentiation of B cells, is a candidate diagnostic and predictive biomarker for antibody-mediated rejection (ABMR).
Shenghui Wu, Xiaojun Su, Qianyu Ye, Qianyu Ye, Yongcheng Wei, Yifang Gao, Yifang Gao, Mingchuan Huang, Yanxu Chen, Jiali Wang, Qiang Zhang, Qian Fu, Jun Li, Chenglin Wu, Huiting Huang, Bowen Xu, Huanxi Zhang, Longshan Liu, Longshan Liu, Longshan Liu, Changxi Wang, Changxi Wang, Changxi Wang   +22 more
doaj   +1 more source