Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BK-beta-1-subunit leads to progressive hearing loss [PDF]
, 2005 The large conductance voltage- and Ca2+-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of cochlear inner hair cells.
Arntz, Claudia +18 more
core
The Development of a Single Frequency Place in the Mammalian Cochlea: The Cochlear Resonance in the Mustached Bat Pteronotus parnellii [PDF]
, 2003 Cochlear microphonic potentials (CMs) were recorded from the sharply tuned, strongly resonant auditory foveae of 1- to 5-week-old mustached bats that were anesthetized with Rompun and Ketavet.
Drexl, Markus +4 more
core +2 more sources
Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai +7 more
wiley +1 more source
SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells [PDF]
, 2009 Cochlear hair cells use SK2 currents to shape responses to cholinergic efferent feedback from the brain. Using SK2-/- mice, we demonstrate that, in addition to their previously defined role in modulating hair cell membrane potentials, SK2 channels are ...
Adelman, John P. +8 more
core +1 more source
Selective deletion of cochlear hair cells causes rapid age-dependent changes in spiral ganglion and cochlear nucleus neurons [PDF]
, 2015 During nervous system development, critical periods are usually defined as early periods during which manipulations dramatically change neuronal structure or function, whereas the same manipulations in mature animals have little or no effect on the same ...
Hume, Clifford +8 more
core +2 more sources
Experimental Study on the Correlation between the Tubar Stenosis and the Professional Deafness [PDF]
, 1953 It has long been a clinically and experimentally well recognized fact that the hearing organs of man and animal would be impaired by the excessive sound stimuli.
Tanaka, Keiichi
core +1 more source
Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling
eLife, 2015 The sensory and supporting cells (SCs) of the organ of Corti are derived from a limited number of progenitors. The mechanisms that regulate the number of sensory progenitors are not known.
Sung-Ho Huh +2 more
doaj +1 more source
Data for: Organ of Corti vibrations are dominated by longitudinal motion in vivo
, 2022 Sebastiaan W. F. Meenderink
openalex +1 more source
On the origins of the compressive cochlear nonlinearity [PDF]
, 2011 Various simple mathematical models of the dynamics of the organ of Corti in the mammalian cochlea are analysed. The models are assessed against their ability to explain the compressive nonlinear response of the basilar membrane.
Champneys, AR +5 more
core
Distribution of aspartate and glutamate in cochlear nucleus (CN) following destruction of organ of Corti (OC) [PDF]
, 1980 R. Thalmann +3 more
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