Results 101 to 110 of about 17,899 (265)
Food Frontiers, Volume 6, Issue 5, Page 2422-2436, September 2025.Isoquercitrin (IQ), a major bioactive compound in buckwheat (Fagopyrum esculentum Moench; BW), serves as a key mediator of the protective effects of BW against noise‐induced hearing loss (NIHL) by activating the Nrf2/HO‐1 signaling pathway, and oral administration of BW and IQ significantly attenuates oxidative stress and hair cell apoptosis through ...
Hojin Lee +6 more
wiley +1 more source
Phytotherapy Research, Volume 39, Issue 9, Page 4046-4059, September 2025.ABSTRACT Deregulation of the mechanistic target of the rapamycin (mTOR) pathway plays an important role in cancer genesis and progression, making it an attractive target for cancer treatment. Disrupting the mTOR pathway contributes to uncontrolled cell growth, increased proliferation, and enhanced cell survival, all of which are hallmarks of cancer ...
Sonali Khanal +9 more
wiley +1 more source
Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling
eLife, 2015 The sensory and supporting cells (SCs) of the organ of Corti are derived from a limited number of progenitors. The mechanisms that regulate the number of sensory progenitors are not known.
Sung-Ho Huh +2 more
doaj +1 more source
Aging Cell, Volume 24, Issue 9, September 2025.Aged CD11b+ cells exhibit impaired IRF7 activation and reduced SNARE protein expression, leading to delayed interferon responses and diminished cytokine secretion. These dual deficits may contribute to the heightened susceptibility of older individuals to severe outcomes following SARS‐CoV infection.
Yu‐Xuan Wu +10 more
wiley +1 more source
Land Degradation &Development, Volume 36, Issue 14, Page 4809-4826, 30 August 2025.ABSTRACT Over the past 60 years, changes in the European agricultural sector have driven migration flows from rural to urban areas, resulting in land abandonment and soil degradation. Rural, nature‐based tourism and outdoor recreation can help reverse negative trends, with growing academic interest in cycle tourism for its economic and social ...
Monica C. M. Parlato, Andrea Pezzuolo
wiley +1 more source
Structure and Mechanics of Supporting Cells in the Guinea Pig Organ of Corti
PLoS ONE, 2012 The mechanical properties of the mammalian organ of Corti determine its sensitivity to sound frequency and intensity, and the structure of supporting cells changes progressively with frequency along the cochlea. From the apex (low frequency) to the base (
Deborah E. Zetes, J. Tolomeo, M. Holley
semanticscholar +1 more source
Dexamethasone uptake in the murine organ of Corti with transtympanic versus systemic administration
Journal of Otolaryngology - Head & Neck Surgery, 2013 ObjectiveTo investigate glucocorticoid uptake in auditory hair cells following transtympanic versus systemic administration of dexamethasone.Study designControlled experimental study.SettingTranslational science experimental laboratory.MethodsSwiss ...
A. Grewal +3 more
semanticscholar +1 more source
Neural Plasticity, 2018 Inner ear formation requires that a series of cell fate decisions and morphogenetic events occur in a precise temporal and spatial pattern. Previous studies have shown that transcription factors, including Pax2, Sox2, and Prox1, play important roles ...
Shaofeng Liu +10 more
doaj +1 more source
I. The organ of corti in mammals [PDF]
Proceedings of the Royal Society of London, 1876 I have divided my subject into three parts, namely, I. The Structure, II. The Innervation, III. The Development of the Organ of Corti concluding with a few remarks on its function, the mode of preparation employed, and the nature of the animals examined. Part I.—The Structure of the Organ of Corti.
openaire +1 more source