Results 11 to 20 of about 62,689 (299)
RSC advances, 2020 Limitations of the current tools used in the drug development process, cell cultures, and animal models have highlighted the need for a new powerful tool that can emulate the human physiology in vitro. Advances in the field of microfluidics have made the realization of this tool closer than ever.
Ilka, Maschmeyer, Sofia, Kakava
+5 more sources
Bioengineering, 2023 This paper presents an innovative experimental setup that employs the principles of audio technology to subject adherent cells to rhythmic vertical vibrations.
Dongho Kwak +3 more
doaj +1 more source
Human Organs-on-Chips for Virology [PDF]
Trends in Microbiology, 2020 While conventional in vitro culture systems and animal models have been used to study the pathogenesis of viral infections and to facilitate development of vaccines and therapeutics for viral diseases, models that can accurately recapitulate human responses to infection are still lacking.
Tang, H. +6 more
openaire +4 more sources
Micromachines, 2021 The understanding that systemic context and tissue crosstalk are essential keys for bridging the gap between in vitro models and in vivo conditions led to a growing effort in the last decade to develop advanced multi-organ-on-a-chip devices.
Yoel Goldstein +7 more
doaj +1 more source
Bioprinters for organs-on-chips [PDF]
Biofabrication, 2019 Abstract Recent advances in bioprinting technologies have enabled rapid manufacturing of organ-on-chip models along with biomimetic tissue microarchitectures. Bioprinting techniques can be used to integrate microfluidic channels and flow connections in organ-on-chip models.
Amir K Miri +5 more
openaire +2 more sources
Bioengineering, 2022 Developing novel drug formulations and progressing them to the clinical environment relies on preclinical in vitro studies and animal tests to evaluate efficacy and toxicity.
Hanieh Gholizadeh +6 more
doaj +1 more source
Microfluidic Organ-on-a-Chip Devices for Liver Disease Modeling In Vitro
Micromachines, 2022 Mortality from liver disease conditions continues to be very high. As liver diseases manifest and progress silently, prompt measures after diagnosis are essential in the treatment of these conditions.
Perizat Kanabekova +2 more
doaj +1 more source
Three-Dimensional-Bioprinted Liver Chips and Challenges
Applied Sciences, 2022 Drug testing, either on animals or on 2D cell cultures, has its limitations due to inaccurate mimicking of human pathophysiology. The liver, as one of the key organs that filters and detoxifies the blood, is susceptible to drug-induced injuries ...
Sajjad Rahmani Dabbagh +3 more
doaj +1 more source
Standardization of Organ-on-Chip: the way forward
, 2023 Presentation slideset describing the need for standards and open platform technology in organ-on-chip. In addition highlights the Translational Organ-on-Chip Platform as a prime example of an open platform.
Andries van der Meer (503130)
core +2 more sources
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2022 Microfluidic chip systems have been an area of interest for lab-on-a-chip and organ-on-a-chip studies in recent years. These chips have many advantages such as high efficiency, low sample consumption, fast analysis, durability and low cost.
Fatma Doğan Guzel +2 more
doaj +1 more source