Results 31 to 40 of about 298,035 (357)

Pushing the boundaries of innovation: the potential of ex vivo organ perfusion from an interdisciplinary point of view

Frontiers in Cardiovascular Medicine, 2023
Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid organs with primary application in allogeneic organ transplantation.
Jasper Iske, Jasper Iske, Andreas Schroeter, Andreas Schroeter, Samuel Knoedler, Samuel Knoedler, Timo Z. Nazari-Shafti, Timo Z. Nazari-Shafti, Leonard Wert, Leonard Wert, Maximilian J. Roesel, Maximilian J. Roesel, Maximilian J. Roesel, Felix Hennig, Felix Hennig, Adelheid Niehaus, Christian Kuehn, Christian Kuehn, Christian Kuehn, Fabio Ius, Fabio Ius, Volkmar Falk, Volkmar Falk, Volkmar Falk, Volkmar Falk, Moritz Schmelzle, Arjang Ruhparwar, Arjang Ruhparwar, Arjang Ruhparwar, Axel Haverich, Axel Haverich, Axel Haverich, Christoph Knosalla, Christoph Knosalla, Christoph Knosalla, Stefan G. Tullius, Florian W. R. Vondran, Bettina Wiegmann, Bettina Wiegmann, Bettina Wiegmann   +39 more
doaj   +1 more source

Flow competition between hepatic arterial and portal venous flow during hypothermic machine perfusion preservation of porcine livers [PDF]

, 2012
Hypothermic machine perfusion (HMP) is regarded as a better preservation method for donor livers than cold storage. During HMP, livers are perfused through the inlet blood vessels, namely the hepatic artery (HA) and the portal vein (PO.
Debbaut, Charlotte, Hillewaert, Wim, Laleman, Wim, Monbaliu, Diethard, Pirenne, Jacques, SAINZ-BARRIGA, MAURICIO, Segers, Patrick   +6 more
core   +2 more sources

Hemoglobin-Based Oxygen Carriers: Potential Applications in Solid Organ Preservation

Frontiers in Pharmacology, 2021
Ameliorating graft injury induced by ischemia and hypoxia, expanding the donor pool, and improving graft quality and recipient prognosis are still goals pursued by the transplant community.
Min Cao, Guoqing Wang, Hongli He, Ruiming Yue, Yong Zhao, Lingai Pan, Weiwei Huang, Yang Guo, Tao Yin, Lina Ma, Dingding Zhang, Xiaobo Huang   +11 more
doaj   +1 more source

Future aspects of renal transplantation [PDF]

, 1988
New and exciting advances in renal transplantation are continuously being made, and the horizons for organ transplantation are bright and open. This article reviews only a few of the newer advances that will allow renal transplantation to become even ...
A Kawaguchi, A Palmer, A. G. Tzakis, B Kahan, E Reed, FO Belzer, H Sollinger, H Tighe, I Koyama, J Chehimi, JM McCord, L Makowka, L Makowka, L Makowka, L. Makowka, NA Halasz, R. Shapiro, RJ Taylor, RY Calne, S Todo, S Todo, T Rosenthal, T. E. Starzl, TE Starzl, TE Starzl, TE Starzl, W. B. Lopatin   +26 more
core   +1 more source

Organ preservation strategies: Review of literature and their applicability in developing nations

South Asian Journal of Cancer, 2014
There has been a change in practice in locally advanced laryngopharyngeal cancers toward non-surgical treatment modalities. Although, there have been landmark trials pertinent to organ preservation, their applicability in developing nations is a topic of
Mitali Dandekar, Anil D′Cruz
doaj   +1 more source

Trends in organ preservation [PDF]

Transplant International, 2003
Organ preservation aims to provide a viable graft with primary function post-transplant. The current basis of preservation for transplantation is static cold storage using specific preservation solutions which minimise cellular swelling and membrane pump activity, thus maintaining cellular ATP levels. The current organ shortage and consequent expansion
McLaren, A, Friend, P
openaire   +2 more sources

Revolutionizing deceased donor transplantation: How new approaches to machine perfusion broadens the horizon for organ donation

Transplantation Reports
Solid organ transplantation is lifesaving for persons with end-stage organ disease. Thanks to advancements in organ preservation, surgeons are now able to successfully transplant organs that were previously considered high risk for poor graft function ...
Stephanie Almeida, William Snyder, Mita Shah, Jonathan Fisher, Christopher Marsh, Alana Hawkes, Diana Gorial, Sean DeWolf, Dianne B. McKay   +8 more
doaj   +1 more source

Successful transplantation of porcine liver grafts following 48-hour normothermic preservation.

PLoS ONE, 2017
Current cold storage organ preservation technique fails to preserve marginal donor grafts sufficiently. Evidence from large animal experiments suggests superiority of normothermic machine preservation of liver allografts.
Thomas Vogel, Jens G Brockmann, David Pigott, Desley A H Neil, Anand S Rathnasamy Muthusamy, Constantin C Coussios, Peter J Friend   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Current practice and novel approaches in organ preservation

Frontiers in Transplantation, 2023
Organ transplantation remains the only treatment option for patients with end-stage organ failure. The last decade has seen a flurry of activity in improving organ preservation technologies, which promise to increase utilization in a dramatic fashion ...
Ozge Sila Ozgur, Ozge Sila Ozgur, Bat-Erdene Namsrai, Timothy L. Pruett, John C. Bischof, Mehmet Toner, Mehmet Toner, Erik B. Finger, Korkut Uygun, Korkut Uygun   +9 more
doaj   +1 more source