Results 31 to 40 of about 116,719 (337)

A Potential Route to Reduce Ischemia/Reperfusion Injury in Organ Preservation

Cells, 2022
The pathophysiological process of ischemia and reperfusion injury (IRI), an inevitable step in organ transplantation, causes important biochemical and structural changes that can result in serious organ damage. IRI is relevant for early graft dysfunction
Marc Micó-Carnero, Mohamed Amine Zaouali, Carlos Rojano-Alfonso, Cristina Maroto-Serrat, Hassen Ben Abdennebi, Carmen Peralta   +5 more
doaj   +1 more source

Organ Preservation Solutions in Transplantation: A Literature Review

Experimental and Clinical Transplantation, 2021
Renal transplant with ABO-incompatible donors expands the donor pool. Earlier studies have focused the use of protocol biopsies in ABOincompatible transplant patients. Our study described outcomes of indication (for cause) renal biopsies and clinical outcomes in patients with ABO-incompatible renal transplant.This retrospective study included 164 ...
Samara Guilhermina, de Sousa, Giulia Vitória, Nascimento da Silva, Ana Maria, Costa Rodrigues, Tereza Maria, Meireles Fernandes da Silva, Felipe Cruz, Costa, Amanda, Freitas Teixeira da Silva, Bernardo Felipe, Santana de Macedo, Marcus Vinicius Henriques, Brito   +7 more
openaire   +2 more sources

Pushing the boundaries of innovation: the potential of ex vivo organ perfusion from an interdisciplinary point of view

Frontiers in Cardiovascular Medicine, 2023
Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid organs with primary application in allogeneic organ transplantation.
Jasper Iske, Jasper Iske, Andreas Schroeter, Andreas Schroeter, Samuel Knoedler, Samuel Knoedler, Timo Z. Nazari-Shafti, Timo Z. Nazari-Shafti, Leonard Wert, Leonard Wert, Maximilian J. Roesel, Maximilian J. Roesel, Maximilian J. Roesel, Felix Hennig, Felix Hennig, Adelheid Niehaus, Christian Kuehn, Christian Kuehn, Christian Kuehn, Fabio Ius, Fabio Ius, Volkmar Falk, Volkmar Falk, Volkmar Falk, Volkmar Falk, Moritz Schmelzle, Arjang Ruhparwar, Arjang Ruhparwar, Arjang Ruhparwar, Axel Haverich, Axel Haverich, Axel Haverich, Christoph Knosalla, Christoph Knosalla, Christoph Knosalla, Stefan G. Tullius, Florian W. R. Vondran, Bettina Wiegmann, Bettina Wiegmann, Bettina Wiegmann   +39 more
doaj   +1 more source

Hemoglobin-Based Oxygen Carriers: Potential Applications in Solid Organ Preservation

Frontiers in Pharmacology, 2021
Ameliorating graft injury induced by ischemia and hypoxia, expanding the donor pool, and improving graft quality and recipient prognosis are still goals pursued by the transplant community.
Min Cao, Guoqing Wang, Hongli He, Ruiming Yue, Yong Zhao, Lingai Pan, Weiwei Huang, Yang Guo, Tao Yin, Lina Ma, Dingding Zhang, Xiaobo Huang   +11 more
doaj   +1 more source

Cold Storage Media versus Optisol-GS in the Preservation of Corneal Quality for Keratoplasty: A Systematic Review

Applied Sciences, 2022
Optisol-GS is the most widely used pharmaceutical composition to preserve corneas for transplantation. This systematic review investigated the effects of different cold corneal storage media (CCSM) compared with Optisol-GS on the quality of stored ...
Izabela Gimenes, Andréa V. Braga Pintor, Mariana da Silva Sardinha, Guido A. Marañón-Vásquez, Marcelo Salabert Gonzalez, Octavio Augusto França Presgrave, Lucianne Cople Maia, Gutemberg Gomes Alves   +7 more
doaj   +1 more source

Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model

Cells, 2022
Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs. This study aimed to compare the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan ...
Yinan Guo, Franka Messner, Sarah E. Beck, Marcos Iglesias Lozano, Hubert Schwelberger, Yichuan Zhang, Kai Kammers, Byoung Chol Oh, Elizabeth D. Greene, Gerald Brandacher, Kelvin G. M. Brockbank   +10 more
doaj   +1 more source

Melatonin in preservation solutions prevents ischemic injury in rat kidneys.

PLoS ONE, 2022
Transplantation is lifesaving and the most effective treatment for end-stage organ failure. The transplantation success depends on the functional preservation of organs prior to transplantation.
Abdurrahman Coskun, Cumhur Yegen, Serap Arbak, Wafi Attaallah, Omer Gunal, Merve Acikel Elmas, Yasemin Ucal, Ozge Can, Banu Baş, Zeynep Yildirim, Ismail Seckin, Sibel Demirci, Mustafa Serteser, Aysel Ozpinar, Ahmet Belce, Gulcin Basdemir, Derya Emel Moldur, Ecenur Izzete Derelioglu, Tahir Koray Yozgatli, Yigit Erdemgil, Ibrahim Unsal   +20 more
doaj   +1 more source

Comparison of Celsior and Perfadex lung preservation solutions in rat lungs subjected to 6 and 12 hours of ischemia using an ex-vivo lung perfusion system

Clinics, 2012
OBJECTIVE: This study evaluated the performance of lungs that were preserved with different solutions (Celsior, Perfadex or saline) in an ex vivo rat lung perfusion system.
Arteiro Queiroz Menezes, Paulo Manuel Pêgo-Fernandes, Paulo Francisco Guerreiro Cardoso, Karina Andrighetti de Oliveira Braga, Natalia Aparecida Nepomuceno, Rogerio Pazetti, Aristides Tadeu Correia, Mauro Canzian, Jacqueline Klarosk Santim, Fabio Biscegli Jatene   +9 more
doaj   +1 more source

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

Cell Transplantation, 2019
Solid organ transplantation was one of the greatest medical advances during the past few decades. Organ preservation solutions have been applied to diminish ischemic/hypoxic injury during cold storage and improve graft survival.
Yimeng Chen, Jian Shi, Terry C. Xia, Renfang Xu, Xiaozhou He, Ying Xia   +5 more
doaj   +1 more source

New solutions in organ preservation

Transplantation Reviews, 2002
Over the last 20 years, a number of methods and solutions have been developed to preserve donor organs for transplantation. Collins et al first introduced the simple cold-storage technique to store and transport kidneys up to 30 hours. The development of the University of Wisconsin cold-storage solution (UW-CSS) in 1986 improved organ preservation and ...
'THart, N, Leuvenink, H, Ploeg, R
openaire   +2 more sources