Results 31 to 40 of about 2,364,274 (318)

Mapping trust relationships in organ donation and transplantation: a conceptual model

open access: yesBMC Medical Ethics, 2023
The organ donation and transplantation (ODT) system heavily relies on the willingness of individuals to donate their organs. While it is widely believed that public trust plays a crucial role in shaping donation rates, the empirical support for this ...
María Victoria Martínez-López   +9 more
doaj   +1 more source

Applications, advancements, and challenges of 3D bioprinting in organ transplantation.

open access: yesBiomaterials Science
To date, organ transplantation remains an effective method for treating end-stage diseases of various organs. In recent years, despite the continuous development of organ transplantation technology, a variety of problems restricting its progress have ...
Guobin Huang   +8 more
semanticscholar   +1 more source

Infection in Organ Transplantation

open access: yesAmerican Journal of Transplantation, 2017
The prevention, diagnosis, and management of infectious disease in transplantation are major contributors to improved outcomes in organ transplantation. The risk of serious infections in organ recipients is determined by interactions between the patient ...
J. Fishman
semanticscholar   +1 more source

Macrophages in Organ Transplantation

open access: yesFrontiers in Immunology, 2020
Current immunosuppressive therapy has led to excellent short-term survival rates in organ transplantation. However, long-term graft survival rates are suboptimal, and a vast number of allografts are gradually lost in the clinic.
F. Ordikhani   +4 more
semanticscholar   +1 more source

Tolerogenic dendritic cells in organ transplantation

open access: yesTransplant International, 2020
Dendritic cells (DCs) are specialized cells of the innate immune system that are characterized by their ability to take up, process and present antigens (Ag) to effector T cells. They are derived from DC precursors produced in the bone marrow.
J. Ochando   +4 more
semanticscholar   +1 more source

Single-Cell Profiling of Kidney Transplant Recipients With Immunosuppressive Treatment Reveals the Dynamic Immune Characteristics

open access: yesFrontiers in Immunology, 2021
Kidney transplantation is currently the first choice of treatment for various types of end-stage renal failure, but there are major limitations in the application of immunosuppressive protocols after kidney transplantation.
Yongguang Liu   +18 more
doaj   +1 more source

Donor and transplant candidate selection for solid organ transplantation during the COVID-19 pandemic

open access: yesAmerican Journal of Transplantation, 2020
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2), a novel coronavirus responsible for a worldwide pandemic has forced drastic changes in medical practice in an alarmingly short period of time.
N. T. Galván   +17 more
semanticscholar   +1 more source

HDAC6 inhibition: a significant potential regulator and therapeutic option to translate into clinical practice in renal transplantation

open access: yesFrontiers in Immunology, 2023
Histone deacetylase 6 (HDAC6), an almost exclusively cytoplasmic enzyme, plays an essential role in many biological processes and exerts its deacetylation-dependent/independent effects on a variety of target molecules, which has contributed to the ...
Qian-qian Zhang   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

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