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Significance of stereologically spatiotemporal cells in molecular medicine [PDF]
Clinical and Translational MedicineSpatiotemporal distributions of intracellular elements (e.g., small molecules, proteins and organelles) dynamically altered in response to extracellular stimuli and pathogens, regulating those element movements, remodelling, and functions independently ...
Xuanqi Liu +5 more
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Impact of Porphyrin Binding to GENOMES UNCOUPLED 4 on Tetrapyrrole Biosynthesis in planta
Frontiers in Plant Science, 2022 Plant tetrapyrrole biosynthesis (TPS) provides the indispensable chlorophyll (Chl) and heme molecules in photosynthetic organisms. Post-translational mechanisms control the enzymes to ensure a balanced flow of intermediates in the pathway and synthesis ...
Vincent Fölsche +5 more
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Opioids Regulate the Immune System: Focusing on Macrophages and Their Organelles
Frontiers in Pharmacology, 2022 Opioids are the most widely used analgesics and therefore have often been the focus of pharmacological research. Macrophages are the most plastic cells in the hematopoietic system.
Shaohua Wen +11 more
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Brain Ultrastructure: Putting the Pieces Together
Frontiers in Cell and Developmental Biology, 2021 Unraveling the fine structure of the brain is important to provide a better understanding of its normal and abnormal functioning. Application of high-resolution electron microscopic techniques gives us an unprecedented opportunity to discern details of ...
Patrick C. Nahirney, Marie-Eve Tremblay
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Current Protocols in Protein Science, 2006 AbstractThis unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre +3 more
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Podophyllotoxin Exposure Affects Organelle Distribution and Functions in Mouse Oocyte Meiosis
Frontiers in Cell and Developmental Biology, 2021 Podophyllotoxin (POD) is one of the most characterized lignans that is commonly found in podophyllum, and its preparations and derivatives are widely used in clinical treatment due to strong antitumor and antivirus activities.
Ping-Shuang Lu +4 more
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Current condition of immune response types
Лечащий Врач, 2021 The article discloses a modern definition of the immune response. The phylogenesis of immunity constitutes a single system and is an integral part of the development of multicellular microorganisms. The emergence of multicellular organisms contributed to
D. A. Sizov, N. Yu. Rukina
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Cell Structure and Function, 2019 In research on cell biology, organelles have been a major unit of such analyses. Researchers have assumed that the inside of an organelle is almost uniform in regards to its function, even though each organelle has multiple functions. However, we are now facing conundrums that cannot be resolved so long as we regard organelles as functionally uniform ...
Kanae Sasaki, Hiderou Yoshida
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Protection against Toxoplasma gondii cysts in pigs immunized with rROP2 plus Iscomatrix
Revista Brasileira de Parasitologia Veterinária, 2020 This study aimed to evaluate the humoral immune response in pigs immunized intranasally and intramuscularly with recombinant Toxoplasma gondii rROP2 protein in combination with the adjuvant Iscomatrix. Twelve mixed breed pigs divided into three groups (n=
Ivo Alexandre Leme da Cunha +7 more
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How neurons maintain their axons long-term: an integrated view of axon biology and pathology
Frontiers in Neuroscience, 2023 Axons are processes of neurons, up to a metre long, that form the essential biological cables wiring nervous systems. They must survive, often far away from their cell bodies and up to a century in humans.
Gaynor Smith +3 more
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