Results 21 to 30 of about 249,615 (265)

Bioanalysis of Eukaryotic Organelles [PDF]

open access: yesChemical Reviews, 2013
The function of biological cells is intimately associated with their internal organization, in which multiple subcellular structures have specialized roles. Such subcellular structures hold the secrets to normal cellular function, progression of disease, and the universe of interactions among biomolecules that define life.
Chad P, Satori   +6 more
openaire   +3 more sources

Organic Fluorescent Probes for Monitoring Micro-Environments in Living Cells and Tissues

open access: yesMolecules, 2023
As a vital parameter in living cells and tissues, the micro-environment is crucial for the living organisms. Significantly, organelles require proper micro-environment to achieve normal physiological processes, and the micro-environment in organelles can
Rui Yang   +11 more
doaj   +1 more source

High Temperature Disrupts Organelle Distribution and Functions Affecting Meiotic Maturation in Porcine Oocytes

open access: yesFrontiers in Cell and Developmental Biology, 2022
Heat stress (HS) has been known to cause reproductive failure in animals, especially in summer. HS severely affects the developmental potential of oocytes and leads to low fertility rates.
Song-Hee Lee   +6 more
doaj   +1 more source

Organelle Inheritance Control of Mitotic Entry and Progression: Implications for Tissue Homeostasis and Disease

open access: yesFrontiers in Cell and Developmental Biology, 2019
The Golgi complex (GC), in addition to its well-known role in membrane traffic, is also actively involved in the regulation of mitotic entry and progression. In particular, during the G2 phase of the cell cycle, the Golgi ribbon is unlinked into isolated
Fabiola Mascanzoni   +2 more
doaj   +1 more source

Circadian Organelles: Rhythms at All Scales

open access: yesCells, 2021
Circadian clocks have evolved in most light-sensitive organisms, from unicellular organisms to mammals. Consequently, a myriad of biological functions exhibits circadian rhythmicity, from behavior to physiology, through tissue and cellular functions to ...
Rona Aviram, Yaarit Adamovich, Gad Asher
doaj   +1 more source

The Lysosome Signaling Platform: Adapting With the Times

open access: yesFrontiers in Cell and Developmental Biology, 2019
Lysosomes are the terminal degradative compartment of autophagy, endocytosis and phagocytosis. What once was viewed as a simple acidic organelle in charge of macromolecular digestion has emerged as a dynamic organelle capable of integrating cellular ...
Subothan Inpanathan, Roberto J. Botelho
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Comparative Structural and Functional Analyses of the Fusiform, Oval, and Triradiate Morphotypes of Phaeodactylum tricornutum Pt3 Strain

open access: yesFrontiers in Plant Science, 2021
The diatom Phaeodactylum tricornutum is a marine unicellular microalga that exists under three main morphotypes: oval, fusiform, and triradiate. Previous works have demonstrated that the oval morphotype of P.
Ludovic Galas   +8 more
doaj   +1 more source

Cartography of an organelle [PDF]

open access: yesNature Methods, 2007
Peptide counting in mass spectrometry allows researchers to draw a quantitative proteomic map of the ER and Golgi.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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