Results 31 to 40 of about 307,002 (301)

Organic Fluorescent Probes for Monitoring Micro-Environments in Living Cells and Tissues

Molecules, 2023
As a vital parameter in living cells and tissues, the micro-environment is crucial for the living organisms. Significantly, organelles require proper micro-environment to achieve normal physiological processes, and the micro-environment in organelles can
Rui Yang, Tao Zhu, Jingyang Xu, Yuang Zhao, Yawei Kuang, Mengni Sun, Yuqi Chen, Wei He, Zixing Wang, Tingwang Jiang, Huiguo Zhang, Mengmeng Wei   +11 more
doaj   +1 more source

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells [PDF]

, 2008
The protein product of the ocular albinism type 1 gene, named OA1, is a pigment cell-specific G protein-coupled receptor exclusively localized to intracellular organelles, namely lysosomes and melanosomes.
Bennett, DC, Venturi C, Palmigiano, A, Schiaffino, MV, Piccirillo, R, Altimare D., Rotondo G., Tacchetti, C, Marigo, V, Bagnato P., Coppola M., Rotondo, G, Venturi, C, Sviderskaya, EV, Palmisano I., Palmigiano A., Altimare D, Bagnato, P, Marigo V., Surace, EM, Altimare, D, Tacchetti C, Innamorati G., Venturi C., Surace E. M., Palmisano I, Rotondo G, INNAMORATI, Giulio, BALLABIO, ANDREA, Schiaffino M. V., Sviderskaya E. V., Palmigiano A, Innamorati G, SURACE, Enrico Maria, Sviderskaya EV, Piccirillo R, Bagnato P, Ballabio A., Incerti B, Piccirillo R., Tacchetti C., Schiaffino MV, Coppola, M, Incerti, B, Bennett DC, Incerti B., Palmisano, I, Coppola M, Bennett D. C., Innamorati, G, Ballabio, A, Marigo V   +51 more
core   +1 more source

High Temperature Disrupts Organelle Distribution and Functions Affecting Meiotic Maturation in Porcine Oocytes

Frontiers in Cell and Developmental Biology, 2022
Heat stress (HS) has been known to cause reproductive failure in animals, especially in summer. HS severely affects the developmental potential of oocytes and leads to low fertility rates.
Song-Hee Lee, Ming-Hong Sun, Dongjie Zhou, Wen-Jie Jiang, Xiao-Han Li, Geun Heo, Xiang-Shun Cui   +6 more
doaj   +1 more source

A RNA-Targeted Two-Photon Bioprobe with High Selective Permeability into Nuclear Pore Complexes for Dynamically Tracking the Autophagy Process among Multi-Organelles

, 2019
Dynamic tracking of the spatiotemporal coordination among various organelles to in-depth understanding of the mechanism of autophagy have attracted considerable attention. However, the monitor of nucleoli participation in autophagy was somehow neglected.
Weiju Zhu (7524980), Xiaojiao Zhu (1974691), Huihui Zhang (2302009), Lin Kong (1401778), Aidong Wang (785120), Hong Li (20183), Junjun Wang (147321), Gang Liu (81776), Hongping Zhou (547918)   +8 more
core   +1 more source

Tracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe [PDF]

, 2018
BODIPY derivative, SF-1, exclusively shows a fluorescence ON response to HOCl and images endogenously generated HOCl in RAW 264.7 macrophages. Widefield and super resolution structured illumination microscopy images confirm localization in the Golgi ...
Sreedharan, S., Smythe, C.G., Das, A., Amitava Das, Sunil Aute, Ali, F., Jim A. Thomas, Saeed, H.K., Carl G. Smythe, Sreejesh Sreedharan, Thomas, J.A., Aute, S., Firoj Ali, Hiwa K. Saeed, H. A. Anila, Anila, H.A.   +15 more
core   +1 more source

Bimodal dynamics of granular organelles in primary renin-expressing cells revealed using TIRF microscopy [PDF]

, 2017
Renin is the initiator and rate-limiting factor in the renin-angiotensin blood pressure regulation system. Although renin is not exclusively produced in the kidney, in nonmurine species the synthesis and secretion of the active circulatory enzyme is ...
Dun, Alison R., Buckley, Charlotte, Bellamy, Christopher, Peter, Audrey, Mullins, John J., Duncan, Rory R., Gross, Kenneth W.   +6 more
core   +1 more source

Organelle Inheritance Control of Mitotic Entry and Progression: Implications for Tissue Homeostasis and Disease

Frontiers in Cell and Developmental Biology, 2019
The Golgi complex (GC), in addition to its well-known role in membrane traffic, is also actively involved in the regulation of mitotic entry and progression. In particular, during the G2 phase of the cell cycle, the Golgi ribbon is unlinked into isolated
Fabiola Mascanzoni, Inmaculada Ayala, Antonino Colanzi   +2 more
doaj   +1 more source

The Lysosome Signaling Platform: Adapting With the Times

Frontiers in Cell and Developmental Biology, 2019
Lysosomes are the terminal degradative compartment of autophagy, endocytosis and phagocytosis. What once was viewed as a simple acidic organelle in charge of macromolecular digestion has emerged as a dynamic organelle capable of integrating cellular ...
Subothan Inpanathan, Roberto J. Botelho
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

viruses replication organelles

, 2023
Positive-sense single-stranded RNA viruses significantly reshape intracellular membranes to generate viral replication organelles that form a controlled niche in which nucleic acids, enzymes, and cofactors accumulate to assure an efficient replication of
Debora Stelitano, Stelitano, D, Mirko Cortese, Cortese, M   +3 more
core   +1 more source