Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Recovery of Organic and Amino Acids from Sludge and Fish Waste in Sub Critical Water Conditions
The possibility of organic and amino acid production from the treatment of sludge and fish waste using water at sub critical conditions was investigated. The results indicated that at sub-critical conditions, where the ion product of water went through a
Muhammad Faisal +2 more
doaj +2 more sources
Evaluation of Wine Fermentation Characteristics of Guizhou’s Five Specialty Fruits Based on the Composition of Organic Acids and Polyphenols [PDF]
To evaluate the fermentation potential of Guizhou’s specialty fruits, the contents of organic acids and polyphenols juices in juices and laboratory prepared wines from crystal grapes, brier grapes, kiwifruits, golden prickly pears and blueberries grown ...
CHEN Qiuzhu, XIE Hanyi, HE Jiaojiao, WU Fang, WANG Chunxiao
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Organic chemical signatures of New Zealand carbonate concretions and calcite fracture fills as potential fluid migration indicators [PDF]
Macroscopic calcite crystals are common in sedimenta¬ry strata, occurring both as tectonic veins and also filling one or more generations of septarian rupture or later brittle fractures in calcareous concretions.
Nelson, Campbell S., Pearson, Michael J.
core
Direct Reversible Decarboxylation from Stable Organic Acids in Solution [PDF]
Many classical and emerging methodologies in organic chemistry rely on carbon dioxide extrusion to generate reactive intermediates for subsequent bond-forming events.
Duanyang, Kong +4 more
core +2 more sources
State-of-the-Art Recovery of Fermentative Organic Acids by Ionic Liquids: An Overview
The main achievements of liquid–liquid extraction (LLE) of fermentative organic acids from their aqueous sources using a diverse range of ionic liquids are summarized since the first study appeared in 2004.
Tonova Konstantza
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Research Program for Organic Food and Farming in Finland [PDF]
The Finnish Ministry of Agriculture and Forestry started a three-year Research Programme on Organic Food and Farming in 2003. The programme consists of 15 projects on different themes covering the whole food chain and has an annual budget of about 2.2 ...
Nykaenen, Arja, Nykänen, Arja
core
HPLC analysis of phenolics / organic acids.
(a) Phenolic / organic acids in CFS of Loig. coryniformis BCH-4. (b) Standards of phenolics / organic acids. (DOCX)
Iqra Gill (13190013) +9 more
core +1 more source

