Results 121 to 130 of about 24,839 (187)

Organic Cation Transporter 2 (OCT2/SLC22A2) Gene Variation in the South African Bantu-Speaking Population and Functional Promoter Variants. [PDF]

OMICS, 2017
Wilson NC, Choudhury A, Carstens N, Mavri-Damelin D.   +3 more
europepmc   +1 more source

Pharmacogenomic insights into OCT1, OCT3 Variants Affecting Metformin Efficacy in Type 2 Diabetes: A Systematic Review and Meta-Analysis

Endocrinology Research and Practice
Type 2 diabetes mellitus (T2DM) poses a significant global health burden, particularly in India. Metformin is the first-line therapy for T2DM; however, substantial interindividual variability in glycemic response remains a clinical challenge.
Varsha Iranna Dalal
doaj  

Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins. [PDF]

Drug Metab Dispos, 2015
Yin J, Duan H, Shirasaka Y, Prasad B, Wang J.   +4 more
europepmc   +1 more source

Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K.

Am J Physiol Renal Physiol, 2019
Yin J, Wagner DJ, Prasad B, Isoherranen N, Thummel KE, Wang J.   +5 more
europepmc   +1 more source

Identification of high-risk SNPs in SLC22A transporter genes: their potential role in PCOS and metformin uptake. [PDF]

BMC Genom Data
Harini R, Usha B, Satish R, Akshatha P, Vijaya Kumar TM.   +4 more
europepmc   +1 more source

Identification of Brimonidine as a Novel Substrate of Organic Cation Transporters OCT2 and MATE1 Expressed in Human Eye. [PDF]

Invest Ophthalmol Vis Sci
Kölz C, Neul C, Hofmann U, Dressler JC, Süsskind D, Wissinger B, Schwab M, Nies AT.   +7 more
europepmc   +1 more source

Organic cation transporter novel 1 (OCTN1): beyond an ergothioneine transporter. [PDF]

Cell Commun Signal
Guo Y, Zhou K, Zhang J, Tao Z.
europepmc   +1 more source

The Molecular Mechanisms of Metformin's Action on Blood Lipid Profile in Diabetic Patients. [PDF]

Int J Mol Sci
Dettlaff-Pokora A, Swierczynski J.
europepmc   +1 more source

Regulation of Human Renal Transporters by Pregnancy-Related Hormones in Primary Proximal Tubular Epithelial Cells. [PDF]

Metabolites
Tsang YP, Wang K, Kelly EJ, Mao Q, Unadkat JD.   +4 more
europepmc   +1 more source

Ion channel and biophysical properties of extracellular vesicles. [PDF]

J Biol Chem
Sanghvi SK, Singh H.
europepmc   +1 more source