FEBS Letters, EarlyView.We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring +6 more
wiley +1 more source
PERTANIAN ORGANIK SUATU ALTERNATIF PENGELOLAAN EKOSISTEM SAWAH YANG SEHAT, ALAMI DAN RAMAH LINGKUNGAN [PDF]
, 2014 Rice crops are the main food crops in Indonesia. In efforts to increase rice productivity , there are still many obstacles such as pest nuisance problem .
Hadi, Mochamad +3 more
core +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Is organic farming inefficient, or are indicators of economic performance of agriculture incomplete? [PDF]
, 2003 Organic farming is expected to alleviate the environmental burden of agriculture, since it rules out the use of chemicals such as synthetic fertilizers, pesticides, herbicides.
Huhtala, Anni
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Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms [PDF]
, 1994 Organic contaminants are readily bioaccumulated by aquatic organisms. Exposure to and toxic effects of contaminants can be measured in terms of the biochemical responses of the organisms (i.e. molecular biomarkers).
Förlin, L. +2 more
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Performance of UK wastewater treatment works with respect to trace contaminants [PDF]
, 2013 This is the post-print version of the final paper published in Science of Total Environment. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Brian Ellor +7 more
core +1 more source
Industrial Organic Chemicals. Starting Materials and Intermediates
Molecules, 1999 n ...
Shu-Kun Lin
doaj +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Ingestion of microplastics by the chironomid Chironomus sancticaroli and effects on the microbiome in the presence of PBDEs [PDF]
, 2016 Microplastic particles in the environment can associate with persistent organic pollutants (POPs) due to the hydrophobic nature of plastics and organic chemicals. PBDEs (polybrominated diphenyl ethers) are widely used as flame-retardants in products such
Disner, Rodrigo G. +8 more
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