Results 61 to 70 of about 1,598,383 (361)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The Tagish Lake chondrite and the interstellar parent body hypothesis [PDF]

, 2001
Investigation of the solvent extractable organic compounds in Tagish Lake. The results are used to test the interstellar parent body hypthesis for the origin of extraterrestrial organic ...
Gilmour, I., Pearson, V. K., Sephton, Mark   +2 more
core  

Study of the trace metal ion influence on the turnover of soil organic matter in cultivated contaminated soils [PDF]

, 2006
The role of metals in the behaviour of soil organic matter (SOM) is not well documented. Therefore, we investigated the influence of metals (Pb, Zn, Cu and Cd) on the dynamic of SOM in contaminated soils where maize (C4 plant) replaced C3 cultures. Three
Benedetti, Marc F., Bermond, Alain, Dumat, Camille, Quenea, Katelle, Toinen, S.   +4 more
core   +2 more sources

Stereoselective synthesis of tetra- and tri-substituted alkenyl nitriles via aminative ring-opening of cyclopropenes with iron-aminyl radical

Nature Communications
The ring opening of cyclopropenes provides a compelling platform for the rapid synthesis of various polysubstituted acyclic alkenes. However, radical-mediated reactions of this type remain underexplored, and none of the existing methods have successfully
Qian Wang, Jin-Kai Cheng, Shi-Xiong Tang, Kendall N. Houk, Fei Wang   +4 more
doaj   +1 more source

Design, Synthesis, and Acaricidal Activity of 2,5-Diphenyl-1,3-oxazoline Compounds

Molecules
By using a scaffold hopping/ring equivalent and intermediate derivatization strategies, a series of compounds of 2,5-diphenyl-1,3-oxazoline with substituent changes at the 5-phenyl position were prepared, and their acaricidal activity was studied ...
Yuming Chen, Jiarui Tian, Yuhao Tan, Yuxiu Liu, Qingmin Wang   +4 more
doaj   +1 more source

Organization Still Matters [PDF]

International Journal of E-Politics, 2017
Use of social media by political parties has become a part of their communication strategies. In Catalonia, where around 20% of Internet users obtain political information through Facebook and Twitter, parties use these channels widely. This article has examined 814 posts, 5,772 comments, 52,470 likes and 25,907 shares from the official Facebook pages ...
Borge, Rosa, Esteve Del Valle, Marc
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Chiral macrocycles forming high-affinity host-guest homoternary complexes for chiral discrimination and amplified circularly polarized luminescence

Nature Communications
The development of macrocyclic hosts with high-affinity 1:2 recognition capabilities is crucial for advancing supramolecular chemistry and its applications.
Rong Fu, Fang-Yuan Chen, Le Dai, Dai-Yuan Li, Qing-Yu Zhao, Si-Dan Guo, Zi-Hang Song, Li-Bo Jing, Heng Wang, Xiaopeng Li, Dong-Sheng Guo, Kang Cai   +11 more
doaj   +1 more source

Mechanical-robust and recyclable polyimide substrates coordinated with cyclic Ti-oxo cluster for flexible organic solar cells

npj Flexible Electronics, 2022
With the rapid development of flexible optoelectronic devices, recyclability is highly desirable for alleviating resource waste and environmental pollution, but remains challenging.
Guangcong Zhang, Qiaomei Chen, Chengcheng Xie, Yongmei Wang, Chaowei Zhao, Chengyi Xiao, Yen Wei, Weiwei Li   +7 more
doaj   +1 more source