Results 81 to 90 of about 378,729 (334)

An exploratory study of mechanisms to transfer and embed a value-based culture : a thesis presented in partial fulfillment of the requirements for the degree Masters of Business Studies in Management at Massey University, Albany, New Zealand [PDF]

open access: yes, 2016
This exploratory study seeks to build on the work of theorists who have proposed concepts to enhance organisational culture through a better alignment of values.
Wallace, Andrew Mark
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Can models of organizational change help to understand ‘success’ and ‘failure’ in community sentences? Applying Kotter’s model of organizational change to an Integrated Offender Management case study [PDF]

open access: yes, 2017
A number of nationally driven initiatives have led to significant changes in the framework of community sentences, with various agencies being required to work in ‘joined-up’ multi-agency arrangements.
Cornish, Neil, Hopkins, Matt, King, Sam
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A cross-cultural study into peer evaluations of women\u27s leadership effectiveness

open access: yes, 2008
Purpose: The present paper is based on a cross-cultural exploration of middle managers in two diverse cultures and aims to focus on how the leadership styles of managerial women are perceived and evaluated. In particular, female and male peer evaluations
Jogulu, Uma D., Wood, Glenice J.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Managerial Factors and Organisational Commitment: A Comparative Study of Police Officers and Civilian Staff [PDF]

open access: yes, 2001
Civilian workers have become a progressively larger proportion of UK Police Forces employment yet there is very little research on this group of workers and none other than this article that compares and contrasts civilian and police officers experience ...
Dick, Gavin P.M., Metcalfe, Beverley
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

School climate and teachers’ organisational commitment in South African high schools

open access: yesInterdisciplinary Journal of Education Research
Previous research on teachers’ organisational commitment reveals that investigations into this subject have yet to focus on school climate and on what undermines or strengthens high school teachers’ commitment.
Segun Emmanuel Adewoye   +1 more
doaj   +1 more source

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