Results 61 to 70 of about 3,553,762 (351)

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Clarifying the impacts of organizational silence on organizational commitment with controlling the effects of organizational rumors [PDF]

open access: yesManagement Science Letters, 2018
Organizational commitment plays an essential role on the success of service businesses as well as municipalities. One of the primary challenges on such firms is to face with rumors and silence, properly. In fact, organizational rumors and silence are two
Mohammad Hozouri   +2 more
doaj   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

open access: yesMolecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Effects of Organizational Justice on Organizational Commitment

open access: yesInternational Journal of Economics and Financial Volues, 2016
Organizational justice has been considered as an important contributor for commitment of employees towards their organization. Only two dimensions (Distributive and procedural justice) of organizational justice were focused in this study.  This research study is cross sectional in design.
Rahman, Asim   +4 more
openaire   +5 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Nurses’ professional competency and organizational commitment: Is it important for human resource management?

open access: yesPLoS ONE, 2017
Background Professional competency is a fundamental concept in nursing, which has a direct relationship with quality improvement of patient care and public health.
Abbas Karami   +2 more
semanticscholar   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

The consequences of organizational commitment in education

open access: yesProcedia - Social and Behavioral Sciences, 2011
AbstractFor enhancing quality of education, organizational commitment (OC) provides suitable background and is a vital factor in schools. OC is related to constructs of productivity, organizational performance and service quality. The author examined simultaneously two components of OC namely: 1- Maintaining membership 2- Attachment. Data were obtained
Reihaneh Shagholi   +3 more
openaire   +2 more sources

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

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