Results 41 to 50 of about 112,826 (305)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Identification-commitment inventory (ICI model): confirmatory factor analysis and construct validity

open access: yes, 2010
Organizational commitment, Organizational identification, Confirmatory factor analysis, Structural equation modeling, Elliptical least square solution,
Yepes i Baldó, Montserrat   +9 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The relation of social capital and organizational justice with organizational commitment based on structural equation model among female high school teachers in Isfahan in 2011-12 [PDF]

open access: yesرویکردهای نوین آموزشی, 2012
The purpose of this research was to study the relationship of social capital and organizational justice with organizational commitment. The population was all female high school teachers in Isfahan, that among them 358 were selected via clustered random ...
Mohammad Ali Nadi   +2 more
doaj  

Psychological capital and organizational citizenship behavior among nurses during the COVID-19 epidemic: mediation of organizational commitment

open access: yesBMC Nursing, 2023
Background Nurses’ organizational citizenship behavior, a spontaneous “altruistic work behavior”, may be affected by psychological capital and organizational commitment, but its mechanism is not clear.
Li Zeng   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Proactivity directed toward the team and organization : the role of leadership, commitment and role-breadth self-efficacy [PDF]

open access: yes, 2009
Employees' proactive behaviour is increasingly important for organizations seeking to adapt in uncertain economic environments. This study examined the link between leadership and proactive behaviour.
Alannah E. Rafferty   +5 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Psychological Flexibility, ACT, and Organizational Behavior [PDF]

open access: yes, 2006
This paper offers organizational behavior management (OBM) a behavior analytically consistent way to expand its analysis of, and methods for changing, organizational behavior.
Hayes, Steven C.   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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