Results 61 to 70 of about 65,320 (256)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Relationship between Hospital Nurses’ Perception of Organizational Justice and Organizational Commitment [PDF]
Alexandria Scientific Nursing Journal, 2016 Perception of organizational justice has been related to numerous other organizationalfactors, including organizational commitment. Yet, less is known about mechanisms linkingorganizational justice to organizational commitment. Objective: Investigate the
Rehab Hussein +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Cogent Social SciencesThe main objective of this study is to examine the moderating effect of employees’ national identity on organizational trust and organizational commitment among employees in hotel establishments in the Hail region, of Saudi Arabia. A conceptual model was
Abdullah M. Alomran +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The Effect of Organizational Cynicism on Organizational Commitment among Nurses
Sağlık ve Hemşirelik Yönetimi Dergisi, 2020 INTRODUCTION: This study was conducted to examine the effect of organizational cynicism on organizational commitment on nurses. METHODS: The descriptive and relationship-seeking and cross-sectional study was conducted between January 2018 and June 2019 ...
Yeşim Biçici, Sevgi Nehir
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
DeReMa (Development Research of Management): Jurnal Manajemen, 2015 This study aims to analyze and explain the influence of spiritual leadership to ethical behavior, quality of work life, job satisfaction, organizational commitment and employee performance.
Riane Johnly Pio +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The Relation Between Organizational Health and Organizational Commitment
Mediterranean Journal of Social Sciences, 2013 Modern management understanding considers human resources to be one of the most important assets of the organizations. While a successful organization will care to choose this asset from among the most qualified candidates, it should also endeavor not to lose its existing employees.
Yüceler, A. +2 more
openaire +3 more sources