Results 131 to 140 of about 4,842,709 (257)

The combination of typing and profiling measurement of organizational culture: Validation of the Intensity and Strength Organizational Culture Questionnaire

open access: yes, 2010
The study aimed at assessing the psychometric properties of a new combined typing and profiling measure of organizational culture, the Intensity & Strength Organizational Culture Questionnaire. It was developed in line with (a) Schein’s (1985) theory; (b)
PETITTA, LAURA, BARBARANELLI, Claudio
core  

Perceptions of organizational values and culture at various levels of an organization [PDF]

open access: yes, 2001
Plan BThis research studied the differences in perceptions of specific categories in the organizational culture and values at the three levels of a two-year post secondary educational institution. Two instruments were used in the study.
Vogds, Jean C.
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Influence of Organizational Culture on the Continuous Improvement: Empirical Study at University

open access: yes
In every university organizational culture makes ground for quality management and is directly connected to development. Quality management is an important part of continuous improvement of any organization. It is focused on increasing the organizations’
Kairiša, Ilze   +2 more
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Organizational Culture in the Greek Science and Technology Parks: Implications for Human Resource Management. [PDF]

open access: yes
Introduction Research and technological poles have been also set up in Greek regions but only in the late '80s, introducing local economy into the modern international competitive environment.
Thanos Kriemadis, Theodore Pelagidis
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

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