Results 91 to 100 of about 7,285,576 (328)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
EFFECTS OF ORGANIZATIONAL JUSTICE ON ORGANIZATIONAL COMMITMENT
Bu çalışmanın konusu, Millî Eğitim Bakanlığı'nın okullarında çalışan, aynı düzeyde olan ancak farklı eğitim programları kullanan öğretmenlerin örgütsel bağlılıkları üzerindeki örgütsel adalet algılarının etkilerini araştırmaktır. Bu araştırma ile örgütsel bağlılık bağımlı değişkeni ile örgütsel adalet bağımsız değişkeni ...
openaire +1 more source
Transforming Philanthropic Transactions [PDF]
Evaluates the approach and effectiveness of SVP's first five years working to inspire philanthropy and volunteerism and build organizational capacity among nonprofits.
Alan Preston +2 more
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Effect of organizational justice, respect, trust, and empowerment on job satisfaction and organizational commitment [PDF]
Trust in managers helps to create a positive work environment for nurses, while mistrust in management impacts job satisfaction and organizational commitment (Laschinger & Finegan, 2005).
Adams, Pamela R.
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
This study aims to investigate the impact of the internal control system (Control environment, Communication, Risk management, Control activities and Monitoring) on organizational effectiveness in Jordan.
Buthayna Mahadeen +3 more
semanticscholar +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

