Results 101 to 110 of about 157,953 (310)

The Contingent Value of Organizational Integration [PDF]

open access: yes, 2013
We elaborate the link between organizational design and effectiveness by examining organizational integration and performance in the context of modern manufacturing.
Turkulainen, Virpi, Ketokivi, Mikko
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Work Team Effectiveness: Importance of Organizational Culture, Work Climate, Leadership, Creative Synergy, and Emotional Intelligence in University Employees [PDF]

open access: yes
(1) Background: In university contexts, the effectiveness of work teams is vital for institutional success and the personal development of an institution’s members.
Huancahuire-Vega, Salomón   +9 more
core   +1 more source

Identity dynamics as a barrier to organizational change [PDF]

open access: yes, 2006
This article seeks to explore the construction of group and professional identities in situations of organizational change. It considers empirical material drawn from a health demonstration project funded by the Scottish Executive Health Department, and ...
Ross, Michael T.   +17 more
core   +1 more source

Towards an Integrated Framework for Corporate Entrepreneurship

open access: yesProblemy Zarządzania, 2016
Drawing on a resource-based perspective as well as strategic entrepreneurship theory, this empirical study examines how the performance effect of corporate entrepreneurship is mediated by firm strategy and task contingency regarding key environmental ...
Katarzyna Bratnicka   +1 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Impact of Organizational Justice on Organizational Effectiveness [PDF]

open access: yes, 2012
The study of Organizational Justice has received great attention from the researchers and it has become frequently topic in the field of industrial-organizational psychology.
Kumar, Rajender   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Organizational health assessment: a Romania firm case study [PDF]

open access: yes
Other than measuring units of output or profit to evaluate organization performance, this research develops a new assessment concept, organizational health. The survey of Work Environment Scale as the foundation data for the System-wide Interpretation of
Shaomin Huang, Gerald W. Ramey
core   +2 more sources

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