Results 101 to 110 of about 108,696 (262)
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Strategic planning effectiveness comparative analysis of the Macedonian context
Strategic planning is an important element in the organizational success and the key to effectiveness and overall competitiveness of the organizations.
Bobek Šuklev, Stojan Daberliev
doaj
Organizational learning (OL) is a crucial factor in enhancing organizational effectiveness in dynamic and unstable work environments, with particular significance in the healthcare sector.
Rashad Said Dabwaan Al-Makhlaafi +2 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Organizational Effectiveness [PDF]
openaire +5 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Investigating the effect of ethical principles of cognitive computing in digital marketing on improving organizational reputation (Case study: B2B businesses) [PDF]
Objective: Digital marketing creates an ideal environment for unethical activities, particularly through digital marketing channels that raise privacy concerns among organizations and consumers.
Tahmorath Hasangholipour Yasori +2 more
doaj

