Results 101 to 110 of about 965,427 (305)

Pengaruh Kepemimpinan dan Budaya Organisasi terhadap Efektivitas Kerja Karyawan ( Studi Kasus pada Puskesmas Segiri ) [PDF]

open access: yes, 2014
Formulation of the problem as posed in this study are: "Is there a significant effect of leadership (X1) and organizational culture (X2) on the effectiveness of employees ( Y ), if there is a significant effect of leadership ( X1 ) of the Employee ...
Tandiarrang, S. (Sarlotha)
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Towards an Integrated Framework for Corporate Entrepreneurship

open access: yesProblemy Zarządzania, 2016
Drawing on a resource-based perspective as well as strategic entrepreneurship theory, this empirical study examines how the performance effect of corporate entrepreneurship is mediated by firm strategy and task contingency regarding key environmental ...
Katarzyna Bratnicka   +1 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The effect of organizational culture on CRM success [PDF]

open access: yes, 2013
Copyright @ 2013 EMCIS.The aim of this paper is to develop a theoretical framework exemplifying the effect of organizational culture on the success of Customer Relationship Management (CRM) systems' implementation.
Al Duwailah, F, Ali, M
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Do Organisational Climate and Strategic Orientation Moderate the Relationship Between Human Resource Management Practices and Productivity? [PDF]

open access: yes
Contingency formulations of Human Resource Management (HRM) theory suggest thatthe effectiveness of HRM practices should vary across firms. This study examinedwhether the relationship between HRM practices and productivity in manufacturingcompanies is ...
Andrew Neal, M Patterson, M West
core  

Built to Change: Catalytic Capacity-Building in Nonprofit Organizations [PDF]

open access: yes, 2001
Summarizes the results of a broad survey of programs, and business and nonprofit experts, in the field of organizational ...
Audrey Newman
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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